CRYPTOCOCCOSIS IN ADVANCE STATE OF AIDS AND ITS CHALLENGING THERAPEUTIC REGIMEN: IS IT REALLY CURABLE?
Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2015, Vol 8, Issue 2
Abstract
Cryptococcosis followed by Cryptococcal meningitis (CM) is a deadly disease in an immuno-compromised patient with the complication of advancehuman immunodeficiency virus/AIDS, which comes through an air born virus Cryptococcus neoformans, from bird dropping. Immune reconstitutioninflammatory syndrome is also often associated with this disease. A 10 years study showed a 17% prevalence of CM in a tertiary care hospital, amongwhich 53.1% were infected with AIDS. Treatment guideline is amphotericin B (AmB) and 5-flucytosine or AmB and fluconazole, but the iatrogeniceffect, cost and scarcity of availability of these drugs are the leading cause of mortality due to this disease. Anyhow, various novel therapeuticapproaches have been taken to reduce and/or to prevent the pathogenesis of CM for the sake of mankind.Keywords: Antiretroviral therapy, Seizures, Hypokalemia, Hypomagnisemia.
Authors and Affiliations
Anindya Banerjee, Swetasri Bhattacharya
Keywords
Related Articles
- EP ID EP605622
- DOI -
- Views 64
- Downloads 0
EVALUATION OF EFFECT OF AQUEOUS EXTRACT OF ZINGIBER OFFICINALE ROSCOE (GINGER) ON ACUTE AND CHRONIC INFLAMMATION IN ADULT ALBINO RATS
 Objective: Zingiber officinale (ZO) Roscoe (Ginger) is known to have many medicinal properties. The present study was carried out to evaluate theanti-inflammatory activity of aqueous extract of ginger in adult albino r...
GAS CHROMATOGRAPHY-MASS SPECTROMETRY ANALYSIS, IN VITRO ACTIVITIES, AND IN SILICO MOLECULAR DOCKING OF MAJOR COMPONENTS OF MICHELIA ALBA DC ESSENTIAL OIL AND SCENTED EXTRACTS
Objective: The essential oil and scented extracts of Michelia alba DC. were analyzed by gas chromatography–mass spectrometry (GC–MS) and investigated for antidiabetic activities in vitro and in silico. Methods: The...
IN VITRO ANTIMICROBIAL ACTIVITY AND MOLECULAR CHARACTERIZATION OF BACILLUS AMYLOLIQUEFACIENS ISOLATED FROM SIMILIPAL BIOSPHERE RESERVE, ODISHA, INDIA
Objective: The purpose of our study was to isolate and identify the bacteriocinogenic strain exhibiting broad range antimicrobial activity and to analyze the effect of different culturing conditions on the production of...
EFFECT OF ETHANOLIC EXTRACT OF CYANOTIS CRISTATA LEAVES APPLIED TOPICALLY ON WOUND HEALING IN WISTAR RATS
  Objective: The objective of this study was to assess the effect of ethanolic extract of Cyanotis cristata leaves when applied topically on healing of wound in Wistar rats.Methods: C. cristata leaves were evaluated fo...
A REVIEW ON MEDICINAL PLANTS OF RAJASTHAN HAVING ANTIDIABETIC ACTIVITY
Diabetes is one of the most common chronic diseases in nearly all countries, and continuously increasing in numbers and significance, as changing lifestyles lead to reduced physical activity. Diabetes is the leading caus...