Cryptococcus neoformans: An Opportunistic Pathogen with an Unusual Presentation in a Renal Transplant Recipient

Journal Title: Saudi Journal of Medical and Pharmaceutical Sciences - Year 2017, Vol 3, Issue 7

Abstract

Abstract: Cryptococcal infection is characteristically associated with immunocompromised status. In most cases, the skin lesions represent a sentinel finding for disseminated cryptococcal infection. We describe a case of a 34 year old male, a solid organ transplant recipient (SOT), on immunosuppression, presenting with necrotising fasciitis of right lower limb. On microbiological and histopathological examination, a diagnosis of disseminated cryptococcal infection was made. In this report, we describe the spectrum of disease associated with Cryptococcus, its life cycle, pathogenesis and Immune Reconstitution Inflammatory Syndrome (IRIS). Cryptococcosis is a serious infection among SOT recipients, with diverse clinical features. This report underscores the need for a multidisciplinary clinical research and education from the Indian perspective. Keywords: Cryptococcus, opportunistic, renal transplant

Authors and Affiliations

Nathany Shrinidhi, Sagar Siddharth, Sharma Swati, Prabhu Ravindra, K. E. Vandana

Keywords

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  • EP ID EP391754
  • DOI -
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How To Cite

Nathany Shrinidhi, Sagar Siddharth, Sharma Swati, Prabhu Ravindra, K. E. Vandana (2017). Cryptococcus neoformans: An Opportunistic Pathogen with an Unusual Presentation in a Renal Transplant Recipient. Saudi Journal of Medical and Pharmaceutical Sciences, 3(7), 800-803. https://europub.co.uk/articles/-A-391754