Cuban Ocular Toxoplasmosis Epidemiology Study (COTES): Clinical Features in 279 Patients from Central Cuba

Journal Title: Journal of Clinical Research and Ophthalmology - Year 2016, Vol 3, Issue 2

Abstract

Purpose: To characterize the clinical features of ocular toxoplasmosis (OT) in Central Cuba. Methods: A database at a large regional referral center was searched for patients who, from April 1, 2011 to May 31, 2013, had the potential diagnosis of OT. Inclusion criteria were the clinical diagnosis of OT, characterized by focal retinochoroidal inflammation. Medical records were reviewed to confirm inclusion criteria (visual acuity recorded in decimal form). Results: 279 patients (329 total eyes) were affected with OT. Overall, 66.7% were diagnosed with acquired OT with a mean age of 35.4 years and 1.8% with congenital OT with a mean age of 3.4 years. The time of onset of OT could not be determined in 28.3% (n=79) of patients. Patient clinical presentations were posterior uveitis (72.8 %), quiescent retinochoroiditis (16.1 %), and panuveitis (11.1%). Fourteen percent of patients had a slight decrease (0.9-0.6) in visual acuity, 44.4% a moderate decrease (0.5-0.2), and 41.6% a marked decrease (< 0.1). Conclusion: There exist large numbers of patients with active toxoplasmic uveitis in the Central Cuban region. To our knowledge, this is the first report in the English medical literature describing OT in the Cuban population.

Authors and Affiliations

J Daniel Diaz, Jorge L Jorge L, Idarmes C Pacheco, David C Gritz

Keywords

Related Articles

Intravitreal Bevacizumab Injection Effect in Exudative Age Related Macular Degeneration

Exudative age-related macular degeneration is the most common cause of vision loss of people over the age 60 in the developed countries. The cause is not clear yet, but since Avastin is largely used for the treatment, th...

Case report “Acute Retinal Necrosis or not?”

Acute retinal necrosis (ARN) comprises of epicleritis or scleritis, periorbital pain, uveitis, vitreous opacity, and necrotizing retinitis. ARN is very difficult to make diagnosis if patient have several complicated ocul...

A rare case of bilateral acute retinal necrosis due to varicella zoster virus in a patient of Multiple myeloma

Acute retinal necrosis syndrome (ARN) is a well-defined entity with characteristic clinical picture of progressive intraretinal inflammation and necrosis and is caused by one of the members of the Herpes group of viruses...

Valacyclovir as a Therapeutic Agent in Acute Retinal Necrosis: Two Case Reports

Introduction: Acute retinal necrosis (ARN) is a rare, rapidly progressive viral retinitis. The current standard of care for ARN consists of intravenous acyclovir for 5-10 days, followed by oral acyclovir for an additiona...

Atypical Presentation of Uveal and Conjunctival Melanoma in the Anterior Segment

Ocular melanoma is a rare malignancy arising from melanocytes of the uvea, the conjunctiva, and the orbit. Uveal melanoma is the most common intraocular malignancy in adults, accounting for 85-95% of ocular melanomas [1-...

Download PDF file
  • EP ID EP231166
  • DOI 10.17352/2455-1414.000032
  • Views 97
  • Downloads 0

How To Cite

J Daniel Diaz, Jorge L Jorge L, Idarmes C Pacheco, David C Gritz (2016). Cuban Ocular Toxoplasmosis Epidemiology Study (COTES): Clinical Features in 279 Patients from Central Cuba. Journal of Clinical Research and Ophthalmology, 3(2), 27-33. https://europub.co.uk/articles/-A-231166