Current Treatment Strategy in Langerhans Cell Histiocytosis
Journal Title: Iranian Journal of Blood and Cancer - Year 2010, Vol 2, Issue 2
Abstract
Langerhans cell histiocytosis (LCH) is a rare disorder described as three different entities including eosinophilic granuloma of bone, the Hand-Schuller-Christian syndrome, and Letterer-Siwe disease. LCH is currently classified into single system LCH, and multisystem LCH. Patients with single system LCH have an excellent prognosis, and are mostly treated with local therapy. Multisystem LCH is subdivided into low risk and high risk groups. A 6-week course of PRED/VBL is recommended for all patients with MS-LCH. Further therapy depends on the response to the initial course, and risk group of the patient.
Authors and Affiliations
Milen Minkov
Keywords
Related Articles
- EP ID EP378520
- DOI -
- Views 55
- Downloads 0
Simultaneous Neuroblastoma and Acute Lymphoblastic Leukemia in an Infant
This article has no abstract.
Infusible Platelet Membrane versus Conventional Platelet Concentrate: Benefits and Disadvantages
Blood transfusion centers are under considerable pressure to produce platelet concentrates with a shelf life limit of 3 to 5 days. Many approaches have been investigated experimentally to produce new hemostatically activ...
Prevalence of Diabetes Mellitus in Patients with Transfusion Dependent β Thalassemia
Introduction: Thalassemia is common in Iran. Appropriate therapy for this disease includes a regular blood transfusion and chelation therapy. However, patients will inevitably confront with side effects, particularly iro...
Different Stages of Platelet Adhesion to the Site of Vascular Injury
Platelet activation and adhesion to the site of vascular injury is a dynamic process comprising reversible and irreversible phases. Platelet adhesion typically occurs in a multi-step process similar to the selectin/integ...
An Overview on Platelet-derived Microparticles in Platelet Concentrates: blood collection, method preparation and storage
Preparations of platelet concentrates (PCs) that are stored under blood bank conditions and used for transfusion purposes, appear to be enriched in platelet derived-microparticles (PMPs) with high coagulant activity that...