Current trends of antifungal susceptibility pattern of dermatomycosis in a tertiary care hospital by Etest and VITEK-2 methodologies
Journal Title: IP Indian Journal of Clinical and Experimental Dermatology - Year 2018, Vol 4, Issue 2
Abstract
Dermatomycosis affect the superficial layers of the skin nails and hair and are often caused by dermatophytic molds candida amp non dermatophytic molds However over the last decade an increasing number of non dermatophyte filamentous fungi amp non albicans Candida have been recognized as agents of skin and nail infections in humans producing lesions clinically similar to those caused by dermatophytes Although tissue invasion by them is a rare possibility they are important as a public health problem particularly in the immunocompromised There are limited studies on the efficacy of antifungal agents against dermatophytes This study was conducted to test the efficacy of 3 systemic antifungal agents viz Voriconazole Itraconazole amp Fluconazole using the Etest method and 2 systemic antifungals viz Itraconazole and Voriconazole by VITEK2 Three different species of dermatophytes which were isolated from the clinically suspected cases were Trichophyton mentagrophytes Trubrum and Mgypseum According to the obtained results Itraconazole and Voriconazole showed the lowest MIC range while Fluconazole had the highest MIC range for most fungi tested Determining the resistance pattern is especially necessary to assist clinicians in treating superficial fungal infections more effectively This will minimize side effects and prevent development of antifungal resistance amp treatment failuresKeywords Dermatomycosis Antifungal resistance Etest VITEK2 Voriconazole Itraconazole Fluconazole
Authors and Affiliations
Saurabh Sharma, Ravika Kanish Budhiraja, Roopam Bassi
Keywords
Related Articles
- EP ID EP488869
- DOI 10.18231/2581-4729.2018.0023
- Views 92
- Downloads 0
A study of serum calcium and uric acid levels in Psoriasis
Introduction Psoriasis is one of the most common dermatological conditions seen in daily practice There has been a lot of research on its consideration as a systemic disease with researchers being of the view that the de...
A study of dermatological manifestation of viral exanthems in a tertiary care center
Introduction Viral fevers are now a days common in and around the spring season They involve all system of the body including skin We tried to review possible dermatological manifestation of all suspected and diagnosed c...
Efficacy of autologous platelet-rich fibrin in chronic cutaneous ulcer: a randomized controlled trial
Background: Platelet derived growth factors have been used as topical adjuvant therapy in chronic cutaneous ulcer. However the clinical evidence for effectiveness is limited. Therefore, this study was performed to evalua...
A clinical study of hair manifestations in cancer patients on chemotherapy
Introduction There has been an increase in cancer related morbidities a significant part of it being related to therapies Chemotherapy targets rapidly growing cells like skin hair follicles and nail matrix Hence a signif...
Favre-racouchot syndrome: Case report
It is also known as nodular elastosis with cyst and comedones The pathophysiology of disease causation is unknown the condition may arises due to prolonged sun exposure We report a case of 68 year old male agriculturist...