Cutaneous pythiosis in horses treated with triamcinolone acetonide. Part 1. Clinical characterization
Journal Title: Revista MVZ Cordoba - Year 2016, Vol 21, Issue 3
Abstract
Objective. The objective of the present study was to characterizer clinically of the healing process of cutaneous pythiosis in horses treated with triamcinolone acetonide. Materials and methods. We conducted a descriptive study, not probabilistic, of convenience. 24 horses were used with cutaneous pythiosis confirmed, a group of 12 animals was administered 50 mg of intramuscular injection of triamcinolone acetonide (TG) and the other group was not applied any treatment (CG). They are undergoing clinical and microscopic characterization of the lesion every 4 days until the complete recovery of granuloma in the GT. Being verified decreased fibrin bloody exudate, pruritus, presence of fistulae and output kunkers, likewise radiographic projections were performed to assess the degree of compromise bone and tissue fibrosis. Results. Macroscopically animals GT present progressive decrease in the clinical features of the disease at 16±1.4 days post treatment application. The wound contraction was 100% at 60±3.4 days after application of the treatment in all granulomas of GT, being highly significant (p<0.0001). Radiological monitoring of chronic skin lesions, met invasion to underlying tissues compromising bone structures, characterized by tissue fibrosis, moderate exostosis, bake as osteolysis and osteomyelitis. Neither of the animals in the CG showed improvement in clinical characteristics, and macroscopic of pythiosis and maintained equal to the first day throughout the study. Conclusions. The use of triamcinolone acetonide is a good therapeutic alternative for the treatment of granulomatous Pythiosis wounds in horses with 100% clinical recovery.
Authors and Affiliations
José Cardona-Álvarez, Ph. D *| Universidad de Córdoba, Departamento de Ciencias Pecuarias, Grupo de Estudios e Investigaciones en Medicina de Grandes Animales (MEGA), Montería, Colombia.Correspondencia: cardonalvarez@hotmail.com, Marlene Vargas-Vilória Ph. D| Universidad Federal de Viçosa, Departamento de Medicina Veterinaria, Viçosa, Brasil., Joaquín Patarroyo-Salcedo, Ph. D| Universidad Federal de Viçosa, Departamento de Medicina Veterinaria, Viçosa, Brasil.
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