Cynodon dactylon Rhizome Extract Decreases the Cardiovascular Biomarkers (Cardiac Troponin I And Homocysteine) and Adenosine Deaminase Activity in Streptozotocin-Induced Diabetes Mellitus in Rats
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2017, Vol 6, Issue 4
Abstract
Objective: The aim of this study was to evaluate the plasma changes of cardiac troponin I level (cTnI), homocysteine (Hcy) and the activity of adenosine deaminase (ADA) in the streptozotocin-induced diabetes mellitus and following administration of pure Cynodon dactylon extract in the diabetic rats. Diabetes Mellitus (DM) is known as a metabolic disease which is followed by different blood and tissue complications. Methods: In this research, the cTnI, Hcy and ADA activity was measured in diabetic group after 3-month administration of Cynodon dactylon extract in three 150, 300 and 450 mg/kg doses. Results: The signifcant increase(P<0.01) in cTnl, Hcy and ADA parameters in diabetic (positive control) group was determined in comparison to the control group (negative control) and a signifcant decrease of those ones (P<0.01) in the 450 mg/kg dose of Cynodon dactylon in comparison to the diabetic and control group. Conclusion: In conclusion, frstly heart damage occurs in diabetic rats and secondly the Cynodon dactylon extract tremendously influences the reduction of above-mentioned parameters and usage of dried powder and/or extract of Cynodon dactylon rhizomes in the food of the diabetic cases may play important role in the cardiovascular health and increasing the glucose consumption by cells.
Authors and Affiliations
Kaveh Azimzadeh| Elite Club, Urmia Branch, Islamic Azad University, Urmia, Iran, Farid Digale| Veterinary Medicine, Urmia Branch, Islamic Azad University, Urmia, Iran, Corresponding e-mail: fariddigaleh1@gmail.com
Keywords
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