Cytohistocorrelation of Breast Lesions: An Assessment of Diagnostic Efficacy of FNA as a Tool for Preoperative Diagnosis of Benign and Malignant Breast Lesions
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 5
Abstract
Introduction: A palpable breast mass is the most common presentation of breast lesions in women. FNAC is a minimally invasive technique which provides rapid and accurate diagnosis and serves a cost-effective tool for the diagnosis of breast masses. We conducted a two year study to evaluate the accuracy of FNA in diagnosis of breast masses and to see the correlation of FNAC results with histopathological findings. Materials and Methods: A two year retrospective study was conducted in the Pathology Department of a teaching institute in North east India. The cyto-histo correlation of all the palpable lumps was calculated and sensitivity and specificity of FNA as a diagnostic tool was calculated for benign and malignant lesions taking histopathological study as the gold standard. Results: Of all the cases that came for FNAC with breast lump, histopathology was done in 41 cases only. 25 cases turned out to be malignant and 16 were benign. The most common lesion encountered was Infiltrating duct carcinoma of breast (24 cases) followed by fibroadenoma (11cases). Cytohistocorrelation was positive in 28 cases (68.3%). The correlation for histologically benign lesions was 56.25% while for malignancy (on biopsy), it was 80%.The sensitivity and specificity for malignant lesions were 100% with a positive predictive value (PPV) of 100% and a negative predictive value (NPV) of 80%. Benign lesions had a sensitivity of 100% and a specificity of 86%. PPV and NPV for benign lesions were 80% and 100% respectively. Conclusion: Although a good correlation between cytology and histology was found, particularly for malignant lesions, histopathological examination is important to rule out false positive and false negative cases and remains the gold standard for diagnosis.
Authors and Affiliations
Dowerah Swagata, Deuri Biman Jyoti, Harlalka Munmun
Keywords
Related Articles
- EP ID EP547475
- DOI 10.21276/ijmrp.2017.3.5.011
- Views 81
- Downloads 0
Bacteriological Profile and Their Antibiotic Susceptibility of Isolates of Surgical Site Infection at Tertiary Care Hospital
Introduction: Surgical site infections (SSI) constitute a major public health problem worldwide and are the commonest nosocomial infection after urinary tract infection (UTI). They are responsible for increasing the trea...
The Altered Thrombocytic Count in Patients with Acute Coronary Syndrome with Deformed Habits
Aims: Our study aimed to analyze variation in platelet count in patients with acute coronary syndrome with habits such as smoking, smokeless tobacco and alcoholics. Materials & Methods: Total 300 adult (18 years above) p...
Virtual Patient as a Simulation-Based Learning Tool to Help Students Learn Clinical Reasoning Skills in Medicine
Background: Numerous instructional methods are used in medical education, including interactive lectures, problem-based learning, case-based learning, and bedside teaching. Bedside teaching provides students with a real-...
Histogenetic and Histomorphometric Studies on Developing Skin of Human Foetuses
Background: Gestational age can be estimated on the basis of histological appearance of foetal skin which makes it medicolegally important. Materials & Methods: Fifty human foetuses were equally divided into five groups...
Influence of Online Learning in Medical Education is Neither Disruptive Nor Supplementary: It’s Time to Walk Parallel!
Technology enhanced education; an ever-evolving process is not a novel concept in medical education. The supporters of online learning stated that disruption of Tertiary Education Institutions (TEI) is inevitable and cre...