Cytohistopathological Correlation of Pap Smear and Cervical Biopsy in Diagnosis of Cervical Lesions: A Cross Sectional Hospital Based Study
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 3
Abstract
Abstract: Cervical cancer remains an important health problem for women worldwide after breast cancer. Cervical cytology screening is helpful in detecting over 90% of cytological abnormalities and premalignant conditions. This study was conducted to study various types of cervical lesions and to correlate the cytological with histopathological findings. 120 patients who have undergone pap smears and cervical biopsies were included in the study. After fixation and staining, smears were studied .Cervical biopsies were processed routinely and examined under microscope. Detailed history with clinical examination was performed and the findings were correlated. 13.4 % cases were found to have malignancy in the age group of 21 yrs- 45yrs. Rarely it was observed in >70 years of age. Amongst all cytologically diagnosed cases of chronic cervicitis, 56% correlated histopathologically. Various epithelial cell abnormalities detected in cytological studies were ASCUS(10.5%), LSIL(47%), and HSIL(31%). PAP smear test was found to be equally sensitive to histopathological examination for the early detection of different cervical lesions. However, biopsy can be performed if any abnormalities are detected in PAP smear for correlation and confirmation. Keywords:Pap smear, cytohistopathological, correlation, cervical biopsy, cervical cancer
Authors and Affiliations
Ayushi Narain, Bheema Rao, Priavadhana Rajan Prasaad, Hemalatha Ganapathy
Keywords
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