Cytokines and Lymphoma
Journal Title: Science Insights - Year 2023, Vol 42, Issue 1
Abstract
Currently lymphoma is mainly treated with combination chemotherapy, hematopoietic stem cell transplantation, immunotherapy, and new targeted therapy, but treatment-related drug resistance, recurrence, extranodal and central infiltration, and leukemic transformation are still clinical problems that need to be solved urgently. Studies have shown that cytokines are expressed to varying degrees in lymphoma patients, which are significantly related to the progression of lymphoma, poor prognosis, chemotherapy response, and drug resistance. It has been confirmed that interleukin 6 (IL-6) and IL-10 are highly expressed in all types of lymphoma, and IL-10 is highly expressed in cerebrospinal fluid of central nervous system lymphoma, and both of them indicate poor prognosis. This review discusses the role of cytokines in the development and potential treatment of lymphoma.
Authors and Affiliations
Richard Omer
Keywords
Related Articles
- EP ID EP712606
- DOI https://doi.org/10.15354/si.23.re117
- Views 52
- Downloads 0
Albumin versus Saline in Mortality in Critically Ill Children
High mortality in critically ill patients is a challenge for the intensive care medicine. While different reasons were figured out and corresponding therapeutic protocols were recommended, the actual mortality is still h...
Risk Factors for Men Who Have Sex with Men
It is typical for men who have sex with men (MSM) to have several sexual partners, unstable partners, unprotected sex, or intersex relationships, all of which increase the risk of contracting human immunodeficiency virus...
Combined Repair Surgery for Cleft Lip and Cleft Palate: A 4-Year Clinical Experience
Surgical repair is the only method of treatment for patients with cleft lip or/and palate. The cleft lip surgery is usually done when the child is 3 to 6 months old, while cleft palate repair is done between 2 and 3 year...
Adhere to the Principle “Primum Non Nocere”: A Documentary of the Pioneer Scientist in Labor Pain Control in China
It is hard to avoid risks during daily medical practice. Even though empiricism hurdles the uniformed and standardized procedures, we are still guided by high-graded clinical trials and professional guidelines. Labor pai...
Research Evolution of Digital Museums in China
In this study, a total of 466 articles with the theme of “Digital Museum” published in China National Knowledge Infrastructure (CNKI) from 2000 to 2019 were taken as the research objects. Through the use of CiteSpaceV so...