Cytological Diagnosis of Deep Fibromatosis: A Case Series
Journal Title: PARIPEX-Indian Journal of Research - Year 2016, Vol 5, Issue 6
Abstract
Fibromatosis forms a spectrum of clinico-pathologic entities, characterized by infiltrative proliferation of fibroblasts/ myofibroblasts that lack malignant cytologic features. The present study deals with the cytomorphologic appearance of fibromatosis and its cytologic differential diagnosis. FNAC was performed in 4 cases of fibromatosis with tumorous clinical presentation using a 22-gauge needle and 20ml syringe. Air dried smears stained with MGG were studied. FNAC revealed moderately cellular smears and showed scattered as well as aggregated spindle cells, some of them being embedded in hypocellular dense stromal fragments. The cells were oval to spindle shaped with tapering ends, bipolar nuclei, bland nuclear chromatin and generally inconspicuous nucleoli. Based on morphology and clinical presentation, a diagnosis of fibromatosis was rendered. Histopathological examination confirmed the cytodiagnosis of fibromatosis in every instance. Based on clinical history, physical findings, imaging data and cytologic observations, a correct diagnosis of fibromatosis can be rendered in most instances if one is conversant with the cytologic features.
Authors and Affiliations
ARSH GUPTA, DEEPA RANI
Keywords
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