Cytomorphological Study of Chronic Lymphocytic Thyroiditis
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2018, Vol 7, Issue 5
Abstract
Introduction: Chronic lymphocytic thyroiditis (CLT) is included in non-neoplastic thyroid lesions. These are autoimmune disorders characterized by inflammation of thyroid with variable clinical features of altered thyroid function. It has prevalence rate of 1-4% and incidence of 30-60/100000 population per year. It is more common in middle aged women. There is rise in the incidence and diagnosis of CLT due to iodine supplementation of diet and improved diagnostic techniques respectively. Aims and Objectives: To study clinical presentation and cytological parameters of CLT in detail and study these parameters with respect to cytological grades. Material and Methods: Total 313 cases of CLT diagnosed on cytology were included in the study. FNAC was done using non-aspiration technique. All the cases were analysed for age, sex and clinical presentation. Cytological parameters were studied in detail and based on these parameters, cases were graded as per Bhatia et al’s criteria. Results & Discussion: Clinically all the cases presented with anterior neck swelling, followed by hypothyroid and hyperthyroid symptoms. Amongst cytomorphological parameters, background lymphocytes were noted in all 3 grades with varying percentages of other parameters. Conclusion: Clinical presentation of lymphocytic thyroiditis varies depending on the stage of disease, but careful evaluation of all cytological parameters can make correct diagnosis of CLT.
Authors and Affiliations
Aarti P. Pachrupe
Keywords
Related Articles
- EP ID EP522343
- DOI 10.21088/ijprp.2278.148X.7518.1
- Views 77
- Downloads 0
Study of Ultrasound Guided Fine Needle Aspiration Cytology of Abdominal and Pelvic Masses
Background and Aims: Fine Needle Aspiration (FNA) which is used for making a cytological diagnosis has become an indispensable component of the work-up of many abnormalities. Intra-abdominal masses always remain an enigm...
A Study of Multiple Congenital Anomalies in Fetus and Neonates
Background: Congenital Anomalies are one of the leading causes of paediatric mortality in developed & developing countries. Based on World Health Organization 3 million fetuses and infants are born each year with congeni...
Histopathological Spectrum of Prostatic Lesions with Special Emphasis on Mimickers of Malignancy
Introduction: Blood transfusion saves millions of life around the world. However knowledge regarding the same in the young and healthy population is not adequate. Aims and Objectives: To study the knowledge, attitude and...
A Study of Histopathological Analysis of Endometrium in Abnormal Uterine Bleeding in a Tertiary Care Centre
Context: Abnormal uterine bleeding (AUB) is an important clinical entity in females. Aims: The objective of the study was to study the histopathological (HPE) features of endometrium and to correlate its incidence with a...
Evaluation of Neonatal Thrombocytopenia: Incidence and Causes
Background: Thrombocytopenia is one of the commonly encountered haematological abnormalities in neonates admitted in NICU. Various factors such as ARDS, neonatal sepsis, meconium aspiration syndrome, neonatal hyperbiliru...