Czynniki wpływające na penetrację składników aktywnych przez skórę
Journal Title: Wiadomości Chemiczne - Year 2011, Vol 65, Issue 3
Abstract
This article presents main factors influencing transdermal delivery of active ingredients in cosmetic and pharmaceutical emulsions. The emulsions are widely used as vehicles, because of their excellent solubilizing properties for lipophilic and hydrophilic active ingredients. It is shown that physicochemical properties of the active ingredients (i.e. molecular mass, polarity, lipophilicity), type of emulsion, the droplet size of dispersed phase, kind of emollients, surfactant/co-surfactant system and presence of permeation enhancer may affect the percutaneous absorption.
Authors and Affiliations
M. Jaworska, E. Sikora, J. Ogonowski
Keywords
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