Dasatinib Induced Cardiac TamponadeA Rare Association
Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 2
Abstract
Drug induced cardiac tamponade is rare. Therapy for imatinib resistant Chronic Myeloid Leukaemia (CML) is an emerging challenge in clinical haematology. For such cases treatment with second line tyrosine kinase inhibitors like dasatinib has resulted in improved outcomes. Dasatinib is a second line BCR-ABL tyrosine kinase inhibitor used in the treatment of Imatinib resistant or Imatinib intolerant CML. Dasatinib has been reported to cause severe pericardial effusions in 1% of all patients in clinical studies. We report here a case of Dasatinib induced cardiac tamponade in whom all other causes of pericardial effusion were excluded and whose clinical symptoms as well as effusion showed no recurrence one month after the drug was stopped.
Authors and Affiliations
Sushant Wattal, Mugula Sudhakar Rao, GS Naveen Chandra, U. K. Abdul Razak, K Ranjan Shetty
Keywords
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- EP ID EP332251
- DOI 10.7860/JCDR/2017/24633.9418
- Views 113
- Downloads 0
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