DDAVP Might Reduce the Risk of Preeclampsia in Pregnant Women with VWF Defi ciency

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DDAVP Might Reduce the Risk of Preeclampsia in Pregnant Women with VWF Defi ciency

Journal Title: Turkish Journal of Hematology - Year 2013, Vol 30, Issue 2

Abstract

To the Editor, Preeclampsia is the most common medical disorder of pregnancy [1]. Preeclampsia can present very early in pregnancy with hypertension and proteinuria.Preeclampsia includes a spectrum of clinical symptoms varying from subtle weight gain and swelling of the face and extremities to severe headache, abdominal pain, nausea, vomiting, and visual impairment. Endothelial cell changes along with widespread fi brin deposition in the microvasculature are parts of the proposed pathophysiological changes in this medical condition [1]. Presence of an impaired fi brinolysis pathway along with the overactive coagulation cascade present in the patients with severe preeclampsia can lead to multiple organ dysfunctions [1].

Authors and Affiliations

Alireza Jahromi, Mehran Karimi

Keywords

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EP ID EP111135
DOI 10.4274/Tjh.2012.0044
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