DDSolver: An Add-In Program for Modeling and Comparison of Drug Dissolution Profiles
Journal Title: The AAPS Journal - Year 2010, Vol 12, Issue 3
Abstract
The online version of this article (doi:10.1208/s12248-010-9185-1) contains supplementary material, which is available to authorized users.
Authors and Affiliations
Yong Zhang, Meirong Huo, Jianping Zhou, Aifeng Zou, Weize Li, Chengli Yao, Shaofei Xie
An Investigation into the Importance of “Very Rapid Dissolution” Criteria for Drug Bioequivalence Demonstration using Gastrointestinal Simulation Technology
The Biopharmaceutics Classification System (BCS) is based on the mechanistic assumptions that the rate and extent of oral drug absorption are governed by drug solubility, intestinal permeability, and dissolution rate fro...
Slow Release Formulations of Inhaled Rifampin
Rifampin microspheres were prepared by spray drying using either polylactic acid (PLA) or poly(lactic-co-glycolic acid) (PLGA) polymers in different drug to polymer ratios (90:10 to 5:95, w/w). The in-vitro release chara...
Comparative Pharmacology and Toxicology of Pharmaceuticals in the Environment: Diphenhydramine Protection of Diazinon Toxicity in Danio rerio but Not Daphnia magna
Pharmaceuticals and other contaminants of emerging concern present unique challenges to environmental risk assessment and management. Fortunately, mammalian pharmacology and toxicology safety data are more readily availa...
Corrigendum: Current status of immunologic approaches to treating tobacco dependence: Vaccines and nicotine-specific antibodies
Dopamine D2 Occupancy as a Biomarker for Antipsychotics: Quantifying the Relationship with Efficacy and Extrapyramidal Symptoms
The online version of this article (doi:10.1208/s12248-010-9247-4) contains supplementary material, which is available to authorized users.