Decompensated Liver Cirrhosis Secondary to Iron Overload in Non-Blood Transfusion Dependent Patients with Sickle Cell Disease (SCD): Report of Two Cases
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2015, Vol 5, Issue 11
Abstract
The prevalence of sickle cell disease (SCD) is high in the southwest region of Saudi Arabia. Liver involvement in patients with SCD represents a challenging medical problem in clinical practice and carrying a high morbidity and mortality rates. We reported two cases of young patients (19 year male and 22 year female), both of them were known to be non-blood transfusion SCD patients. They have had almost the same clinical presentation with advanced decompensated liver cirrhosis and severe progressive jaundice. Early screening of SCD patients for iron overload, beside commencement of iron chelating agents can prevent the long-term sequel of iron overload.
Authors and Affiliations
Mohammed Al-Dugdugi, Erwa Elmakki
Keywords
Related Articles
- EP ID EP347174
- DOI 10.9734/BJMMR/2015/13755
- Views 51
- Downloads 0
Evaluation of Commercial Rapid Diagnostic Test Kit for Tuberculosis: Further Evidence Supporting Negative Policy on the Use of Serological Tests for Pulmonary Tuberculosis Diagnosis in Developing Countries
Aim: To know whether one of the commercially available immunochromatographic tuberculosis tests is comparable with the widely available method, direct sputum microscopy. Design: The study prospectively validated the pulm...
Comparison of Diastolic Function of Homozygous Sickle Cell Anaemia with Haemoglobin AA Children Using Basic Mitral Inflow Doppler Echocardiography
Aims: Sickle cell anaemia (SCA) remains the most prevalent and arduous inherited disease in Nigeria. Various adverse cardiovascular consequences have been documented including cardiac chamber enlargement and left ventric...
Calcium and Total Bilirubin Levels in Patients Co-Infected with HIV and Hepatitis C Viruses in Lautech Teaching Hospital, Osogbo, South West Nigeria
Aim: One third of HIV patients are co- infected with HCV. As HIV patients live longer this co-infection and its complications such as liver cirrhosis, hepatic carcinoma, metabolic syndrome are emerging as major manifesta...
Ramsay Hunt Syndrome in HIV Positive Individual
Ramsay-Hunt syndrome (RHS) is caused by varicella zoster virus (VZV) infection in the geniculate ganglion of the facial nerve. It is characterized by facial palsy, otic pain, herpetic vesicles around the auricle and exte...
Acute Effects of Air Stacking Versus Glossopharyngeal Breathing in Patients with Neuromuscular Disease
Objective: To compare the effects of Air Stacking (AS) and Glossopharyngeal Breathing (GPB) on the Maximum Insufflation Capacity (MIC) in patients with Neuromuscular Disease (NMD). Methods: We design a randomized cross-...