Deep Learning to Predicting Live Births and Aneuploid Miscarriages from Images of Blastocysts Combined with Maternal Age

Abstract

Objectives: Making an artificial intelligence (AI) classifier that uses the maternal age and an image of the implanted blastocyst to determine the probability of getting a live birth. Methods: The dataset comprised maternal age data and 407 images of blastocysts which led to live births and 246 images of blastocysts which led to aneuploid miscarriages, matched for maternal age. An AI system using deep learning was developed for predicting the classification and probability of a live birth. Results: The accuracy, sensitivity, specificity, and positive and negative predictive values of the developed AI classifier were 0.75, 0.82, 0.64, 0.79, and 0.68, respectively. The area under the curve was 0.73 ± 0.04 (mean ± standard error). Conclusions: A classifier using AI for a blastocyst image combined with the maternal age showed potential in determining the probability of a live birth.

Authors and Affiliations

Yasunari Miyagi, Toshihiro Habara, Rei Hirata, Nobuyoshi Hayashi

Keywords

Related Articles

A Comparative Analysis of Application of Genetic Algorithm and Particle Swarm Optimization in Solving Traveling Tournament Problem (TTP)

Traveling Tournament Problem (TTP) has been a major area of research due to its huge application in developing smooth and healthy match schedules in a tournament. The primary objective of a similar problem is to minimize...

Utilizing CRISPR as a Novel Tool for the Induction of Cell Reprogramming

Researchers can now target specific DNA sequences and easily modify them thanks to recent developments in CRISPR technology, enabling genome manipulation with unmatched precision. Furthermore, cell reprogramming is one o...

DNA Linear Block Codes: Generation, Error-Detection, and Error-Correction of DNA Codeword

In modern age, the increasing complexity of computation and communication technology is leading us towards the necessity of new paradigm. As a result, unconventional approach like DNA coding theory is gaining considerabl...

A Scalable Algorithm for Interpreting DNA Sequence and Predicting the Response of Killer T-Cells in Systemic Lupus Erythematosus Patients

The incidence and prevalence of SLE in North America are 23.2 and 241 per 100,000 people per year respectively while the incidence in Africa is 0.3 per 100,000 people per year. The study aims to predict the autoimmune re...

Emotion Recognition from Electroencephalogram Signals based on Deep Neural Networks

Emotion recognition using deep learning methods through electroencephalogram (EEG) analysis has marked significant progress. Nevertheless, the complexities and time-intensive nature of EEG analysis present challenges. Th...

Download PDF file
  • EP ID EP724391
  • DOI https://doi.org/10.61797/ijbic.v1i1.132
  • Views 45
  • Downloads 0

How To Cite

Yasunari Miyagi, Toshihiro Habara, Rei Hirata, Nobuyoshi Hayashi (2022). Deep Learning to Predicting Live Births and Aneuploid Miscarriages from Images of Blastocysts Combined with Maternal Age. International Journal of Bioinformatics and Intelligent Computing, 1(1), -. https://europub.co.uk/articles/-A-724391