DENDRITIC ARCHITECTURE: A NEW TOOL FOR DEVELOPMENT OF NOVEL DRUG DELIVERY SYSTEMS
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 2
Abstract
Dendrimers are composed of a multifunctional core molecule attached to polymer branches. Drugs can be inserted between the branches and held until ‘interactions’ release it. Dendrimers are a new class of three-dimensional, man-made molecules produced by an unusual synthetic route which incorporates repetitive branching sequences to create a unique novel architecture. Exceptional features of the dendritic architecture include a high degree of structural symmetry, a density gradient displaying an intra-molecular minimum value and a well defined number of terminal groups which may be chemically different from the interior. The combination of these features creates an environment within the dendrimer molecule facilitates an avenue to developing reliable and economical fabrication and manufacturing of functional nanoscale materials that would have unique properties (electronic, optical, opto-electronic, magnetic, chemical, or biological) that could be the basis of new nanoscale technology and devices.
Authors and Affiliations
Ram Choudhary, P Kumar, K N Jayaveera
Keywords
Related Articles
- EP ID EP155909
- DOI -
- Views 97
- Downloads 0
SOME ETHNO-MEDICINAL PLANTS USED BY THE NATIVE PRACTITIONERS OF CHANDEL DISTRICT, MANIPUR, INDIA
This article highlights some ethno-medicinal plants used by the traditional practitioners of Naga community in khangshim bio – region of Chandel district for the treatment of various ailments. A field survey revealed num...
RECENT POTENTIAL USAGE OF SURFACTANT FROM MICROBIAL ORIGIN IN PHARMACEUTICAL AND BIOMEDICAL ARENA: A PERSPECTIVE
The use and potential commercial application of biosurfactant has increased during the past decade which can be used as emulsifiers, de-emulsifiers, wetting and foaming agents, functional food ingredients and as detergen...
FORMULATION DEVELOPMENT OF IRBESARTAN (POORLY WATER-SOLUBLE DRUG) IMMEDIATE RELEASE TABLETS
The aim of the present study is to increase the solubility of poorly water soluble drug Irbesartan by using surfactants and formulating into immediate release tablets by using super disintegrants. Surfactants such as sod...
ANTIDIABETIC AND ANTIHYPERLIPIDAEMIC EFFECT OF POLYGALA JAVANA DC ON ALLOXAN INDUCED DIABETIC RATS
The ethanol extract of Polygala javana whole plant (Family: Polygalaceae) was investigated for it antidiabetic and antihyperlipidaemic effect in Wistar Albino rats. Diabetes was induced in albino rats by administration o...
EVALUATION OF ANTHELIMINTIC ACTIVITY IN THE BARK OF Homalium zeylanicum
The main aim of the study was to investigate Phytoconstituents and antihelmintic activity in the bark extract of Homalium zeylanicum. All phytochemical screening methods were done by using standards methods, were as anti...