Dengue Sero-surveillance in Delhi: A Community-Based Study
Journal Title: Journal of Communicable Diseases - Year 2017, Vol 49, Issue 4
Abstract
Background: IgG ELISA is useful as an epidemiological tool when used to establish sero-prevalence. Extensive background information is required before selecting sites for dengue vaccine trials like types of dengue virus that are causing disease, preferably over a number of years, sero-prevalence of dengue IgG antibodies, prevalence of each serotype, rates of infection, specific mortality, etc. Aims and Objectives • To study the prevalence of dengue IgG antibodies in the serum of adults in urban slums of Delhi • To study the knowledge, attitude and the practice of study subjects about the prevention of mosquito breeding and dengue fever Methodology: This cross-sectional study was conducted from January 2013 to December 2013 in two urban slums of Delhi, Balmiki Basti and Delhi Gate. All adults aged 20 years and above were included in the study irrespective of sex and previous history of dengue. Knowledge, attitude and practices against mosquito breeding were also taken through predesigned, pretested questionnaires. Results: A total of 49(20.5%) adults from Balmiki Basti and 190 from Delhi Gate were enrolled in the study. Mean IgG dengue OD levels of the study subjects was 1.62±0.568. Of the total, 86% were positive for dengue IgG positivity while 13% negative and 1% equivocal. Of all participants, 214(89.9%) were aware of mode of dengue transmission while 25(10.1%) were not. Majority of the participants 137(57.3%) used liquid vaporizers for prevention of mosquito bites. Discussion: The current study reported that 85.4% of the healthy population in urban slums of Delhi is seropositive for dengue IgG, which indicates the unprecedented extent of exposure to dengue virus. It is 7.8% higher than the study conducted in Delhi in 1998(77.6%). It coincides with the rising trend of dengue cases every year in Delhi, making it an endemic region now.
Authors and Affiliations
Shantanu Sharma
Keywords
Related Articles
- EP ID EP267489
- DOI 10.24321/0019.5138.201731
- Views 83
- Downloads 0
Carbapenemase and NDM-1 Production by Escherichia coli and Klebsiella pneumoniae from Patients belonging to a Rural Community in North India Hospitalized with CommunityAcquired Infections
Carbapenem-resistant Enterobacteriaceae, especially New Delhi metallo-β-lactamase type-1-producing strains, exhibit multidrug resistance, thus posing a serious public health threat for treatment of infections caused by G...
Serum Sickness in Patients Receiving Equine Rabies Immunoglobulin
Background: Equine Rabies Immunoglobulin (ERIG) is being used for treatment of category-III animal bite cases. ERIG is economical as compared to Human Rabies Immunoglobulin (HRIG) and hence more affordable to patients in...
Larvicidal Susceptibility Studies of a few Strains of Aedes Vectors of Bengaluru, Karnataka, India
Objective: To determine the larvicidal activity of four insecticides against different strains of two dengue vectors-Aedes aegypti and Aedes albopictus of Bengaluru. The study thus aims to determine the variation of resi...
Seroprevalence of Hepatitis A Virus (HAV) and Hepatitis E Virus (HEV) Co-infection in the Patients Presenting with Acute Viral Hepatitis Attending a Tertiary Care Hospital in North India
Introduction: Hepatitis A virus (HAV) and Hepatitis E virus (HEV) are both transmitted enterically, resulting in acute viral hepatitis (AVH) in developing countries like India. HAV has a world-wide distribution and affec...
Microbiological Profile of Fungal Keratitis in North-West Rajasthan
Oculomycosis is a major cause of visual impairment, eye pain, redness, discharge, diminution of vision and photophobia are presenting features. We collected corneal scraping from 80 suspected cases of fungal keratitis an...