DEPRESSION AND ITS PHARMACOLOGICAL MANAGEMENT: A CRITICAL REVIEW
Journal Title: Journal of Drug Delivery and Therapeutics - Year 2015, Vol 5, Issue 4
Abstract
Depression is considered as an affective disorder characterized primarily by change of mood. It is associated with significant socioeconomic problems, morbidity and mortality. The prevalence of major depression in the general population is estimated at 5% in world population. Prevalence ranges from 9% in ambulatory medical patients to 30% in hospitalized patients. According to the World Health report approximately 450 million people suffer from a mental or behavioral disorder, yet only a small minority of them receives even the most basic treatment. Currently, the available anti-depressant agents are associated with unwanted side effects and have their own limitations. An increasing number of herbal products have been introduced into psychiatric practice, as alternative or complementary medicines. The added advantages of indigenous medicinal treatment would include its complementary nature to the conventional treatment making latter safer, well tolerated and economical remedy for depressive disorders.
LIQUISOLID COMPACTS: A PROMISING APPROACH FOR SOLUBILITY ENHANCEMENT
At present 40% of the drugs within the development pipelines, and approximately 60 % of the drugs coming directly from synthesis area unit poorly soluble. Solubility is one of the important parameter to obtain desired c...
ANALYSIS & INTERPRETATION OF PREVALENCE OF PREDIABETES WITH SPECIAL REFERENCE TO COIMBATORE
The Diabetes Mellitus patients glucose level alteration results were shown to few extent increased Glucose level with Diabetes Mellitus (18.7 ± 0.0), Type-I Diabetes Mellitus (74.5 ± 2.74), T-II Diabetes Mellitus (76.9...
REDUCTION OF ACRYLAMIDE FORMATION IN POTATO CHIPS BY AQUEOUS EXTRACT OF ROSELLE
Acrylamide (AA) is an industrial chemical formed in some foods; particularly starchy foods, during heating process such as frying, baking and roasting. AA is proven to be carcinogenic in animals and a probable human carc...
METHOD DEVELOPMENT AND VALIDATION OF CLOPIDOGREL DRUG IN THE DRUG SUBSTANCES AND DOSAGE FORM BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY
The present work describes a validated reverse phase high performance liquid chromatographic method for estimation of Clopidogrel in the drug substances and dosage form. The quantification was carried out using Ultron ES...
A PROMISING TECHNIQUE TO IMPROVE THE SOLUBILITY BY LIQUISOLID COMPACTION TECHNOLOGY
About 60-70% of the drugs synthesized are poorly soluble and comes under BCS Class-II&IV. Now it is a challenging situation during the development of different dosage forms for pharmaceutical industries because solubilit...