Dermatological Manifestations in HIV Paediatric Patients and their Relation to Clinico-Immunological Categories in A Tertiary Care Centre
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 9
Abstract
Background: Dermatological manifestations are very common in HIV-related opportunistic events and are usually initial markers of immunodeficiency. Objective: To study the various dermatological manifestations in children with HIV in our institute and to correlate with clinical staging (WHO) and CD4 T-cell count. Material & Methods: This was a hospital based study where HIV positive children were studied for dermatological manifestations over a period of 1 year. Clinical profile and CD4 counts with other lab investigations were performed to derive any correlation. Statistical analysis was done with SPSS software where p value <0.05 was considered significant. Results: Out of 100 children included in this study fifty five were females and forty five males. The predominant mode of transmission of disease was Perinatal transmission (92%). On ART 60.29% subjects and 28.12% subjects not on ART had dermatological manifestations.Non infective lesions when considered as a single entity were also significantly higher when taking ART, which is statistically significant (p value 0.040). Forty percent subjects among HIV stage-I, 48% subjects among stage-II, 100% subjects among stage-III and 50% subjects among stage-IV had dermatological manifestations.The prevalence of Infective lesions in total 18% (p< 0.001), HZ 3%(p< 0.001) and in non infectious lesions toatal 51%, apthous ulcers11%(p< 0.001) was significantly higher when Immunosuppression was severe.Among non-infectious lesions (51%,)papulopruritic lesion,xerosis was the most common followed by aphthous ulceration. Among infectious lesions, scabies was the commonest, followed by candidiasis and molluscum.
Authors and Affiliations
Dr. Y. Kodandapani, Dr. Mendu Suresh Babu, Dr. Taduri Ravi Kumar, Dr. Neetika Ashwani, Dr. Neela Aruna Rekha
Keywords
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- EP ID EP255456
- DOI 10.9790/0853-1609015055
- Views 71
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