Description of the First Case of Mycobacterium tuberculosis Beijing Strain Isolated in Cameroon
Journal Title: Microbiology Research Journal International - Year 2016, Vol 17, Issue 2
Abstract
Aims: Beijing remain the most M. tuberculosis lineage distributed and associated to multidrug resistance known worldwide. Its detection in a young person urge to make a large molecular epidemiology study in the concerned region since this can significantly impact tuberculosis (TB) control and vaccine strategies development. Presentation of Case: In this study, we described the first case of M. tuberculosis Beijing strain isolated from a 20 years old girl in Cameroon. This strain was resistant to Isoniazid, Rifampicin, Streptomycin and Ethambutol. Spoligotyping and MIRU/VNTR genotyping analysis showed that the strain belonged to SIT1. The patient responded well to 12 months drug therapy of 4 KmGfxPtoHCfzEZ / 8 GfxPtoCfzEZ; although she was probably contaminated by her elder sister who died from TB few months before. This case may traduce a transmission event in Cameroon. Conclusion: This was the first study that isolated M. tuberculosis Beijing lineage in Cameroon and showed the importance to purchase a large study in the concerned regions.
Authors and Affiliations
Francioli Koro Koro, Joseph Rodrigue Foe Essomba, Leslie Kaiyven Afi, Yannick Kamdem Simo, Félix Fotso Piam, Mbe Jean Romain, Jurgen Noeske, François-Xavier Etoa, Sara Irène Eyangoh
Keywords
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- EP ID EP350780
- DOI 10.9734/BMRJ/2016/28963
- Views 86
- Downloads 0
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