DESIGN OF MEDICATED TOOTH PASTE FOR DENTAL DISORDERS.

Journal Title: International Journal of Advanced Research (IJAR) - Year 2018, Vol 6, Issue 3

Abstract

In the present work, it was planned to prepare therapeutic medicated dental pastes for treatment of periodontitis and oral thrush, which provides effective treatment. Stress was given on local action of the drug and to treat initial stages of periodontitis and oral thrush. Beclomethasonedipropionate was chosen model drug which was a corticosteroid which has a wide range of anti-inflammatory activity. The prepared dental pastes were subjected for various physicochemical parameters like PH, Spreadability, tube extrudability, uniformity of drug content and IR studies. For this study periodontal infective pus sample of a patient collected from a patient under the supervision of dental professor of a local dental college. In-vitro drug release studies were carried out in PH 6.4 phosphate buffer. Stability studies of selected formulations were also done at ambient temperature (30?C) for the period of six months as per ICH guidelines. The formulations were subjected for primary skin irritation test in healthy human volunteers for 72 hours. In-vitro diffusion study showed good results in formulation F2, which showed more retentive time in oral cavity. During physicochemical studies significant results were obtained and found to be within the limits of official standards. The present work is being focused on designing of medicated tooth pastes to protect the gums, teeth and oral cavity from periodontal infections and oral thrush resulting from improper fixation of artificial dentures. The present study revealed that the prepared Beclomethasonedipropionate dental paste formulations will be useful in the treatment of oral thrush and periodontal diseases of all age groups of patients.

Authors and Affiliations

Kavyashree P Sagare, M Yashwanath Rao, K. Purushotham Rao, Satish K

Keywords

Related Articles

ASSESSING THE RELATIONSHIP BETWEEN ATTITUDE AND AWARENESS REGARDING HIV/AIDS USING CANONICAL CORRELATION ANALYSIS.

The objective of this study is to explore the relation between awareness regarding HIV/AIDS transmission and attitude towards the infected person using canonical correlation analysis. A survey was conducted in Karachi to...

BRIDGING THE GAP OF QUALITY EDUCATION PROVISION IN SECONDARY SCHOOLS: A REFECTION ON EXISTING INSTRUCTIONAL SUPERVISORY PRACTICES.

The impact of instructional supervision in enhancing provision of quality education in learning institutions appears to be in doubt worldwide. The overall objective of the study was to establish the effectiveness of the...

PROTEOMICS IN DENTISTRY- A REVIEW.

Proteomics is the study of proteins, which constitute the building blocks of living matrix, on a large scale. Applications of proteomics have revolutionized various spheres of dental diagnostics, treatment and research....

CONTROL OF REGISTRATION ON LAND BOOKS IN MOROCCAN LAW.

International Journal of Advanced Research (IJAR)

THE FORMER TRADITIONAL AND THE LATER FORMAL: AN EVOLUTIONARY ANALYSIS OF SOCIAL PROTECTION IN GHANA.

This study looks at social protection from the indigenous African point of view and looks at the trajectory it has taken to its current state with reference to current trends in social protection. Social protection has b...

Download PDF file
  • EP ID EP284280
  • DOI 10.21474/IJAR01/6769
  • Views 70
  • Downloads 0

How To Cite

Kavyashree P Sagare, M Yashwanath Rao, K. Purushotham Rao, Satish K (2018). DESIGN OF MEDICATED TOOTH PASTE FOR DENTAL DISORDERS.. International Journal of Advanced Research (IJAR), 6(3), 1081-1086. https://europub.co.uk/articles/-A-284280