Detection of accessory gene regulator groups genes and cassette chromosome mec types among Staphylococcus aureus isolated from intensive care unit patients
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2015, Vol 5, Issue 2
Abstract
Objective: To detect antibiotic resistance pattern, methicillin resistant Staphylococcus aureus (S. aureus), staphylococcal cassete chromosome mec (SCCmec) types and accessory gene regulator (agr) groups among isolates of S. aureus. Methods: Of 78 S. aureus isolates, we performed antibiotic susceptibility test and then, and detected mecA gene, SCCmec types and agr specificity group genes by PCR assay. Results: All the isolates were susceptible to vancomycin and linezolid. The majority of (94.2%) of methicillin resistant S. aureus harbored SCCmec type III. We detected agr group I in 45% and group II in 34.6% of the isolates. The other strains belonged to agr specificity groups III and IV (3.27% and 22.9%, respectively). Conclusions: The majority of (45%) S. aureus isolates belonged to agr specificity group I. There was no statistical significant relationship between agr and antibiotic resistance and/or clinical signs.
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- EP ID EP227272
- DOI 10.1016/S2222-1808(14)60643-5
- Views 48
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