Detection of AmpC-β lactamase Enzymes by AmpC DiscTest
Journal Title: Journal of Medical Sciences - Year 2014, Vol 17, Issue 2
Abstract
Microbes have many mechanisms of unresponsiveness to antimicrobial agents that may arise in them over months or years. Among them, degradation of antibiotics by enzymes is one of the common methods of bacterial resistance, particularly in Enterobacteriaceae.1,2 At least 400 different types of β-lactamases from clinical isolates have been discovered. Broadly they are of three types: extended-spectrum beta-lactamases (ESBLs), Amp C β-lactamases and carbapenemases. AmpC type beta-lactamases are cephalosporinases and hydrolyze penicillins, cephalosporins, except the fourth-generation compounds and monobactams.3,4,5
Authors and Affiliations
Shugufta Roohi, Bashir Ahmad Fomda
Keywords
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