DETECTION OF EPSTEIN - BARR VIRUS IN LYMPHOMA LESIONS AMONG SUDANESE PATIENTS USING LMP-1 MONOCLONAL ANTIBODY
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2014, Vol 3, Issue 6
Abstract
OBJECTIVE: this was a retrospective descriptive study aimed to investigate the association of EBV with different types of lymphoma in Sudanese patients. METHODS: Fifty paraffin-embedded formalin-fixed tissue sections of lymphoma lesions were immunohistochemically stained using latent membrane protein-1 (LMP-1) Monoclonal Antibody and results were analyzed using SPSS version 16. RESULTS: Only two cases were positive for EBV LMP-1, one was NHL B cell type and the other was Hodgkin’s Lymphoma. CONCLUSION: the results do not support considering EBV LMP 1 as a significant prognostic factor for lymphoma in our locality. KEY WORDS: EBV, LMP-1, Lymphoma, Sudan
Authors and Affiliations
Marwa Salah Abdalla Abdelmageed| Department of Histopathology and Cytology, Neelain University, Khartoum, Sudan., Esam Mohamed Abdulraheem| Department of Medical Laboratories, College of Applied Medical Science, Shaqra University, Saudi Arabia., and Babikir Ishag Mohamed Fadul| National Health Laboratory, Ministry of Health, Khartoum, Sudan.
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