Detection of Prom using Strip Immuno Assay Test to Detect Insulin Like Growth Factor Binding Protein-1(IGFBP-1) in Amniotic Fluid in Comparison with Fern Test
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 5
Abstract
Introduction: PROM is an emergency obstetric event necessitating urgent intervention with variable outcome. Leaking of amniotic fluid has manifold obstetric implications depending upon when it occurred? at what gestation? duration of leak and colour of liquor. Study objective included evaluation of methods of detection of PROM and comparing effectiveness of two methods. Material and methods: This study was a Prospective and comparative study conducted on 100 Antenatal women reported with the history of PROM to Government Maternity Hospital, Sulthan Bazaar, Osmania Medical College, Hyderabad from January 2014 to august 2015. Results: The present study of 100 women with PROM, 66 cases had liquor draining clinically and 34 cases were with no obvious draining of liquor clinically. Among these 34 cases, 26 had intact membranes and 8 were without intact membranes So total cases with Ruptured membranes are 74 and with Unruptured membranes were 26. Among the 74 cases with ruptured membranes APT is Positive in 67 cases and negative in 7 cases and Fern test is Positive in 33 cases, negative in 41 cases. P value is <0.000001 which highly significant. Conclusion: Our study shows that APT is more efficacious than FERN test in diagnosing PROM.
Authors and Affiliations
Ushalatha Chalurkar, Ratnam Andallu
Keywords
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