Detection of Virulance Factors and Antibiotics Susceptibilty of Pseudomonas aeruginosa Isolated from Burns and Wounds infections in Ba'quba City.
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2017, Vol 12, Issue 5
Abstract
This study was conducted for the period from 1/11/2015 to 15/6/2016 in Baquba city in Iraq. 74 samples were collected from burns with ten isolate (32.2%), wounds infections with six isolate (13..9%) from Baquba General Hospital. The results showed that 15 isolate (93.75%) were able production Lecithenase . Furthermore, 13(81.25%) isolate were able production Haemolysin,and 14 (87.5%) were able production proteinase .The sensitivily of these isolates were tested against (12) antibiotics. The results showed that the highest resistances were for Amoxicillin ,Ampicillin , Cefotaxime ,Trimethoprime with 100% , while the lowest resistance was for Ciprofloxacin 25% , while it showed high sensitivity toward combination Emipenem with 100% .As well as, 11 isolate(68.75%) were able to production β-lactamase., Furthermore, six isolate (37.5%) were able to production metalloβ-Lactamases. Finally, four isolate (25%) were able to production Extended Spectrumβ-Lactamases enzyme Conclusion: p. aeurginosa isolates highest resistances were Amoxicillin, Ampicillin, Cefotaxime ,Trimethoprime with 100%, While the lowest resistance were for Ciprofloxacin 25%. while it showed high sensitivity toward combination Emipenem with 100% . additionally some of isolates production, β-lactamase, metallo β-Lactamases and Extended Spectrumβ-Lactamases enzyme.
Authors and Affiliations
Ibtihal Hameed Mohsin, Lina A. S. Al-Saadi *, Eman sabbah abd al Rahman*
Keywords
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