DETERMINATION OF ANDROGRAPHOLIDE IN ANDROGRAPHIS PANICULATA EXTRACTS WITH AND WITHOUT HUMAN SERUM BY HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2013, Vol 4, Issue 12
Abstract
Andrographis paniculata (Acanthaceae)commonly known as Kalmegh is used both in Ayurvedic and Unani system of medicines for a number of ailments. Kalmegh contains bitter principles – Andrographolide, 14-deoxy-11, 12- didehydroandrographolide, neoandrographolide, 14-deoxy-11, oxyandrographolide, 14-deoxy-andrographolide, and flavonoids. HPTLC analysis indicates that the maximum amount of andrographolide was present in extracts of Andrographis paniculata prepared by refluxation. Amount of Andrographolide in all extracts with and without serum along with the % recovery is compared and the variation was found to be < 15 %. The HPTLC method developed for estimation of andrographolide is simple, sensitive and accurate.
Authors and Affiliations
Mohan Manvitha
Keywords
Related Articles
- EP ID EP136370
- DOI 10.7897/2230-8407.041209
- Views 122
- Downloads 0
EVALUATION OF DIURETIC ACTIVITY OF MILK EXTRACT OF SEMECARPUS ANACARDIUM NUT
Semicarpus anacardium ‘Marketing Nut’ is a tropical flowering plant widely distributed in India. Semicarpus anacardium are widely used for its therapeutic potential as immunomodulatory and in folklore the plant material...
MICROSCOPICAL AND PHYTOCHEMICAL INVESTIGATION OF ROOT COCOS NUCIFERA LINN.
In the present study, dried and powdered root of Cocos Nucifera linn was extracted with various solvents of increasing polarity. The present study deals with microscopical and phytochemcial investigation. This root consi...
BIOREMEDIATION OF PICOLINE BY ADAPTING P. AERUGINOSA ISOLATED FROM INDUSTRIAL EFFLUENT POLLUTED WATER
Environmental pollution implies any alteration in the surroundings but it is restricted in use especially to mean any deterioration in the physical, chemical, and biological quality of the environment. All types of pollu...
A PRELIMINARY STUDY ON THE EFFECTS OF PETROLEUM ETHER & ALCOHOLIC BARK EXTRACT OF Anthocephalus cadamba (Roxb.) MIQ. IN ACUTE AND CHRONIC IN-VIVO INFLAMMATORY RAT MODELS
In order to appraise the traditional use of Anthocephalus cadamba, the petroleum and alcoholic extracts of stem bark of Anthocephalus cadamba, were investigated for their acute and chronic anti-inflammatory activity. The...
BENZIMIDAZOLES: THE LATEST INFORMATION ON BIOLOGICAL ACTIVITIES
Benzimidazole is a heterocyclic aromatic organic compound. It is an important pharmacophore and a privileged structure in medicinal chemistry. Benzimidazole and its derivatives play an important role in medical field wit...