Determination of Antibacterial Activity of Aqueous Extract of Moringaoleifera Leaves against Escherichia coli, Salmonella typhi and Pseudomonas aeruginosa
Journal Title: Scholars Bulletin - Year 2017, Vol 3, Issue 9
Abstract
Abstract:Medicinal herbs are moving from fringe to mainstream use with a greater number of people seeking for remedies and health approaches from side effects caused by synthetic chemicals. This has aggravated the search for antimicrobials from plants sources. Therefore, this study was aimed at investigating the efficacy of aqueous extract of Moringaoleifera leaves against some clinical isolates (Escherichia coli, Salmonella typhi and Pseudomonas aeruginosa). The study was carried out between January and June, 2014. The Moringaoleifera leaves sample were collected from the Kebbi State University of Science and Technology Aliero Orchard and screened for antimicrobial activity against the isolates using agar well diffusion assay, and preliminary phytochemical analysis were also conducted using standard procedures. Concentrations of the extract used were 30mg, 60mg, 90mg and120mg. The extract demonstrated the highest activity at 120mg, with the zone of inhibition of 28.5mm, 25.5mm and 24.0mm on Salmonella typhi, Escherichia coli and Pseudomonas aeruginosa respectively. The results of preliminary phytochemical screening revealed the presence of Saponins, Tannins, Flavonoids, Glycosides and Alkaloids. The antibacterial assay results portrayed broad spectrum activity of Moringaoleifera leaf extract against the test organisms with the comparable inhibitory zones by standard antibiotic (Ciprofloxacin). In conclusion the results from these findings have shown the antibacterial potentials of Moringaoleifera leaf extract implying that the extract could help as a chemotherapeutic agent or might be a lead compound for the development of new potent antibacterial agents. Keywords:Moringaoleifera, Aacqeous, Extract, Clinical, Isolates
Authors and Affiliations
Manga SS, Isah M, Kalgo MZ, Bazata AY
Keywords
Related Articles
- EP ID EP382590
- DOI -
- Views 101
- Downloads 0
Invasive Modalities in Ocular Drug Delivery: Emphasis on the Posterior Segment Praneeth Kakullamarri
Abstract:Ocular drug delivery to the scientists is a fascinating field because of challenges and exquisite barriers encountered in the ocular milieu. Till now, non-invasive approaches in ocular delivery are not yet succe...
The Use of Gaseous Hydrogen in Spark Ignition Engines
Abstract:The world suffers from air pollution from burning fossil fuels to produce energy. Cars consume a large proportion of fuel, especially spark ignition engines. The pollutants produced by these engines can be reduc...
Mapping out Media-Politics Relationship in Kenya: Comparing the MwaiKibaki-Uhuru Kenyatta Regimes’ Media ownership, Usage and Control
Abstract:Media remains an important institution that continues to transform lives of people in Kenya as in any part of the world. News is a basic need and continues to shape the perceptions of people on issues affecting...
Geothermal Water Potential of Bursa (Turkey) Province
Abstract:In this study, the physico-chemical properties of hot spring water of Bursa province and Erikli cold water were investigated. Erikli cold water is bottled for commercial use. Water samples were collected in-situ...
The Study of Parameters of Daqing Oilfield’s Putaohua Reservoir G1 Block
Abstract:Daqoing Oilfield Putaohua group belong to extend oil --- river delta depositional system, with the dual role of rivers and lakes is characterized by formation heterogeneity clear water distribution complex, form...