Determination of cord blood lipid profile in neonates and its correlation with birth weight and maternal anthropometry
Journal Title: Indian Journal of Child Health - Year 2018, Vol 5, Issue 9
Abstract
Introduction: Serum lipid disorders have their roots in childhood and atherogenic changes are postulated to originate early in life. Cord lipid profile is a useful tool in the earlier detection of babies at a higher risk. Objectives: The objectives of the study were to assess the early onset dyslipidemia by determining cord blood lipid profile in healthy term newborns and to compare the cord blood lipid profile between terms small for gestational age (SGA) and appropriate for gestational age (AGA) newborns. Materials and Methods: This prospective observational study was conducted from October 2013 to October 2014 in the Department of Pediatrics of a Tertiary Care Institution of Central India. All normal term newborns with gestational age between 37 and 42 weeks were included in the study. After thorough examination, their weight, length, and ponderal index (PI) were recorded. Cord blood was collected immediately after the delivery and cord lipid profile was measured. Data were recorded and correlated statistically. Results: Of 114 neonates, 71 were AGA, 40 were SGA, and three were large for gestational age. There were 59 (51.8%) female and 55 (48.2%) male neonates. Birth weight, length, gestational age, head circumference, and PI were significantly higher in AGA neonates than SGA neonates (p<0.001, 0.013, 0.022, 0.02, and <0.001, respectively). Total cholesterol (TC), triglycerides (TGs), low-density cholesterol (LDL), and very low-density cholesterol (VLDL) levels were significantly higher in term SGA than term AGA neonates. Conclusion: Birth weight correlated negatively with LDL, VLDL, TC, and TG. Lipid profile parameters were also higher in babies with maternal body mass index ≥25 kg/m2.
Authors and Affiliations
Shipra Mandraha, Avyact Agrawal, Vikas Talware
Keywords
Related Articles
- EP ID EP472226
- DOI -
- Views 107
- Downloads 0
Study of serum vitamin B12 levels in pregnant mothers and their newborns and its relation to growth of the infants
Introduction: The effect of vitamin B12 deficiency in pregnancy on the growth of infants has not been properly studied. Objectives: To study the correlation of vitamin B12 levels in pregnant mothers with vitamin B12 leve...
Effect of black tea consumption on onset of action of benzodiazepines in children: A case–control study
Introduction: Benzodiazepines (lorazepam and diazepam) are the drugs that have calming effects, but caffeine of black tea is a stimulant. Hence, taking black tea along with benzodiazepines might block the calming effects...
Oral health knowledge and oral hygiene practices of pre-school teachers in a selected region of Kathmandu city
Background: Dental caries and periodontal diseases are the most common oral health problems seen globally. Schools provides an ideal environment for all forms of education, including oral health and teachers can be instr...
Poland syndrome: Atypical presentation and review of literature
Poland syndrome is a rare congenital disorder with absent or hypoplastic pectoralis major and hand anomalies. Dextroposition, female predisposition, and the left-sided anomalies in Poland syndrome are rarely reported in...
Comparing the effectiveness of intranasal Midazolam and intravenous Lorazepam for the treatment of acute seizures in children
Objective: The objective of this study was to compare the safety and efficacy of intranasal midazolam with intravenous lorazepam in acute seizures in children. Methods: Children aged 6 months–12 years with active tonic/c...