Determination of incidence of different Candida spp. in clinical specimens and characterisation of Candida species isolates
Journal Title: Indian Journal of Microbiology Research - Year 2016, Vol 3, Issue 4
Abstract
Aims & Objectives: 1. To isolate and characterize the Candida species from various clinical samples. 2. To determine the spectrum of Candidiasis. 3. To determine the predisposing factors for Candidiasis. Method: This Prospective Analytical study was conducted in the Department of Microbiology of a Teaching Tertiary care Rural hospital of Western India over a period of 1½ years after obtaining Ethical clearance. A total of 1438 samples submitted to department of microbiology for routine diagnostic work up were assessed. A detailed review of history & clinical findings was undertaken. Fifty isolates which fulfilled the diagnostic criteria for Candidiasis were selected, included in the study and subjected to a battery of microbiological investigations aimed at detecting, isolating, identifying and characterizing Candida sp.so as to determine the spectrum of Candidiasis. Results: The incidence rate of Candidiasis in clinical specimens came out to be 35 per thousand samples per year. The species wise distribution of Candida isolates was C.albicans(42%), C.tropicalis(50%), C.glabrata(4%), C.parapsilosis(2%) & C.krusei(2%). Conclusion: Results indicate a significant shift in the species causing invasive Candidiasis away from C.albicans to more resistant Non-albicans species which has important clinical implications.
Authors and Affiliations
Abhishek Mehta, Vidya S. Date
Keywords
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