Determining Risk Factors of Epilepsy in Children with Cerebral Palsy: A Retrospective Study
Journal Title: The Journal of Pediatric Research - Year 2018, Vol 5, Issue 2
Abstract
Aim: The aim of this study is to determine the risk factors of epilepsy development in children with cerebral palsy. Materials and Methods: Data of 234 cerebral palsy patients treated at Ege University Pediatrics Department, Child Neurology Division between January 2008 and December 2015 were evaluated retrospectively. All patients were classified into two groups; Group I: cerebral palsy without epilepsy (n=116) and Group II: cerebral palsy with epilepsy (n=118). The clinical and laboratory findings of the groups were compared to each other, a p value of less than 0.05 was considered as statistically significant. Results: There was no significant difference between the two groups in terms of gender, gestastional age, birth type, birth weight, risk factors for cerebral palsy development (pre-/peri-/postnatal), duration of neonatal intensive care stay and the need for mechanical ventilation (p>0.05). The risk factors of epilepsy were determined as the following; the presence of neonatal convulsions, focal clonic and generalized tonic neonatal seizures, an abnormal baseline rhythm on neonatal electroencephalography (EEG), discharge from neonatal intensive care unit with at least one antiepileptic drug, spastic bilateral (tetraplegic) cerebral palsy, epileptic activity on the sixth month EEG, abnormal cranial magnetic resonance imaging findings, mental retardation, microcephaly and visual problems. Conclusion: Epilepsy is a common problem in children with cerebral palsy. Therefore, cases of cerebral palsy, especially those with the determined risk factors should be closely monitored for epilepsy in order to ensure a timely diagnosis and proper treatment.
Authors and Affiliations
Ferda Gürkan, Sarenur Gökben, Hepsen Mine Serin, Sanem Yılmaz, Gül Aktan, Hasan Tekgül
Keywords
Related Articles
- EP ID EP382403
- DOI 10.4274/jpr.24471
- Views 64
- Downloads 0
Investigations of Microtubule-associated Protein 2 Gene Expression in Spinal Muscular Atrophy
Aim: Spinal muscular atrophy (SMA) is a devastating genetic disease in childhood andff is caused by the absence of functional survival motor neuron (SMN) protein, which leads to impairments of the cytoskeleton, especiall...
Oral Bacteria of Children with Turner Syndrome
Aim: Turner syndrome (TS) is a genetic disorder caused by a numerical or structural aberration of the X chromosome, which is associated with a female phenotype. Concerning oral status, several studies have revealed that...
Pediatric Bilateral Pheochromocytoma and Experience of Laparoscopic Cortical Sparing Adrenalectomy
Pheochromocytomas are neuroendocrine tumors. In this report, we present a 15-year-old girl who had cerebral palsy and pheochromocytoma. She also had a diagnosis of hyperinsulinemic hypoglycemia in her history. She underw...
A Reliability and Validity Study of the Turkish Version of the Parenting Scale
Aim: This study was conducted for the purpose of determining the validity and reliability of the Parenting scale in a Turkish sample. Materials and Methods: The study was conducted as a methodological-descriptive-cross s...
Effect of Fatigue on Quality of Life in Pediatric Oncology Patients
As a result of the medical progress in the field of pediatric oncology, childhood cancers are seen as a chronic life-threatening disease rather than an acute or terminal disease. While methods used in cancer treatment in...