Determining the Sample Size and Power for Cox Regression Analysis
Journal Title: International Journal of Medical and Health Sciences - Year 2015, Vol 4, Issue 4
Abstract
Statistical power is the probability of rejecting a false null hypothesis and a larger sample size will increase the power of test. In the process of computing power, the sample size is determined. Therefore, the power of the study should be determined before starting to work. Cox regression analysis is a popular method of survival analysis and it examines the relationship between survival times and one or more covariates. In this study, power and sample size of cox regression analysis is determined for different situations of parameters by creating of study designs. As results of calculation, the practical tables and suggestions about determining the appropriate sample size were presented to the researches for clinical study.
Authors and Affiliations
Nesrin ALKAN, Yüksel TERZİ, B. Baris ALKAN
Keywords
Related Articles
- EP ID EP39918
- DOI -
- Views 280
- Downloads 0
A rare incidental dual malignancy in Ectopic and Orthotopic Thyroids
Ectopic thyroid tissue may be encountered anywhere from the foramen caecum to the lower neck. It is rarely seen in the mediastinum. True malignant transformation in ectopic thyroid tissue is rare. Cases of ectopic prima...
Clinicopathological Analysis of Benign tumours of the Sinonasal tract
Background: The nasal cavity and the paranasal sinuses form a single functional unit. Sino nasal tumours are characterized by low incidence, nonspecific symptoms, and late presentation. The sinonasal tumours encompass a...
Prediction of perinatal outcome in IUGR Fetuses: Emerging role of MCA-PSV Doppler studies
Objective: To determine the diagnostic performance of fetal Middle cerebral artery (MCA) – Peak Systolic velocity (PSV) for prediction of adverse perinatal outcome in Intauterine growth restriction (IUGR) fetuses and to...
Isolated Duodenal polyp presenting as upper gastrointestinal bleed
Duodenal polyps are rare lesions in patients undergoing upper GI endoscopy (UGIE), and the prevalence varies widely with range of 0.3-4.6% of cases. Duodenal adenomas are most commonly associated with familial adenomato...
Empiric Antibiotic Therapy: Preserving Antibiotics for the Future and Saving Lives
Increasing bacterial resistance to routinely used antibiotics is one of the most important public health issues. In countries like India, where antibiotics are easily available over the counter, self medication and ina...