Determining the Sample Size and Power for Cox Regression Analysis

Journal Title: International Journal of Medical and Health Sciences - Year 2015, Vol 4, Issue 4

Abstract

Statistical power is the probability of rejecting a false null hypothesis and a larger sample size will increase the power of test. In the process of computing power, the sample size is determined. Therefore, the power of the study should be determined before starting to work. Cox regression analysis is a popular method of survival analysis and it examines the relationship between survival times and one or more covariates. In this study, power and sample size of cox regression analysis is determined for different situations of parameters by creating of study designs. As results of calculation, the practical tables and suggestions about determining the appropriate sample size were presented to the researches for clinical study.

Authors and Affiliations

Nesrin ALKAN, Yüksel TERZİ, B. Baris ALKAN

Keywords

Related Articles

Otomycosis : A Clinico Mycological Study

Introduction: Otomycosis is a common fungal infection of the ear that is seen in the tropical and sub tropical regions of the world. Objective: The aim of this study was to determine the prevalence of fungal agents and...

The Epidemiology of Human Breast Cancer

Breast cancer is the most common cancer among women and is the second leading cause of cancer related death. In India 70,000 new cases of breast cancer and 35,000 deaths due to this cancer are reported every year. The e...

Oxidative stress and Antioxidant status in Ghanaians with Type 2 Diabetes Mellitus

An imbalance between reactive oxygen species production and antioxidant scavenging has been implicated in type 2 Diabetes Mellitus (DM). Reports indicate that several complications of Diabetes Mellitus results from incr...

Rheumatoid Arthritis in a case of Primary Biliary Cirrhosis - An unusual Association

Primary biliary cirrhosis is an autoimmune disease that tends to progress to fibrosis and cirrhosis with hepatic failure. Primary biliary cirrhosis is often associated with other non- hepatic autoimmune diseases. A rare...

Efficacy of Bronchoalveolar Lavage In Diagnosing Lung Malignancy

Background: Due to new therapeutic options in thoracic oncology, the pathological diagnosis of bronchial carcinoma has become more challenging. The majority of bronchial cancer is diagnosed from small biopsy specimens a...

Download PDF file
  • EP ID EP39918
  • DOI -
  • Views 278
  • Downloads 0

How To Cite

Nesrin ALKAN, Yüksel TERZİ, B. Baris ALKAN (2015). Determining the Sample Size and Power for Cox Regression Analysis. International Journal of Medical and Health Sciences, 4(4), -. https://europub.co.uk/articles/-A-39918