Development and characterization of a photocurable alginate bioink for three-dimensional bioprinting

Journal Title: International Journal of Bioprinting - Year 2019, Vol 5, Issue 2

Abstract

Alginate is a biocompatible material suitable for biomedical applications, which can be processed under mild conditions on irradiation. This paper investigates the preparation and the rheological behavior of different pre-polymerized and polymerized alginate methacrylate systems for three-dimensional photopolymerization bioprinting. The effect of the functionalization time on the mechanical, morphological, swelling, and degradation characteristics of cross-linked alginate hydrogel is also discussed. Alginate was chemically-modified with methacrylate groups and different reaction times considered. Photocurable alginate systems were prepared by dissolving functionalized alginate with 0.5- 1.5% w/v photoinitiator solutions and cross-linked by ultraviolet light (8 mW/cm2 for 8 minutes).

Authors and Affiliations

H. H. Mishbak, Glen Cooper, P. J. Bartolo

Keywords

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  • EP ID EP678704
  • DOI -
  • Views 170
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How To Cite

H. H. Mishbak, Glen Cooper, P. J. Bartolo (2019). Development and characterization of a photocurable alginate bioink for three-dimensional bioprinting. International Journal of Bioprinting, 5(2), -. https://europub.co.uk/articles/-A-678704