Development and Evaluation of an Aqueous Polymeric Dispersion of Eudragit L 100-55 Using Emulsification Technology
Journal Title: International Journal of Nano Studies & Technology (IJNST) - Year 2013, Vol 2, Issue 5
Abstract
Aqueous polymer dispersions (APD) are preferred on environmental and safety grounds. APD offer several advantages over polymers dissolved in organic solvents including lower spraying viscosities, higher solids loading, higher spray rates, no solvent environmental, toxicity, or flammability issues, and reduced energy requirements. The purpose of this work is to prepare and characterize an aqueous-based pseudolatex dispersion of Eudragit L100-55 using emulsification technology with superior stability. The prepared APD is evaluated on the basis of organoleptic, physical, chemical and in-vitro drug release performance. APD film is prepared by casting method and evaluated. Coating is done over Diclofenac sodium tablet and In vitro drug release profile of APD coated tablet and organic coated tablet is studied and shows better release in case of APD as compared to market formulation and organic coating
Authors and Affiliations
Sanjar Alam
Keywords
Related Articles
- EP ID EP201484
- DOI 10.19070/2167-8685-130007
- Views 98
- Downloads 0
Self-Assembled Microwires of Aromatic Acids and Melamine
Self-assembled micro/nanowires of melamine and seveal aromatic acids, including thiocyanuric acid, trimesic acid, terephthalic acid, and 5-sulfoisophthalic acid, are formed through evaporation of water in a solution mixt...
Removal of Heavy Metals by Indigenous Microorganisms and Identification of Gene Responsible for Remediation
The present study deals with the removal of heavy metals from solid waste disposal sites. The waste generated from the small scale industrial operations such as grinding, milling, cutting, rubbing, painting, washing are...
Review of Nanomedicine
Review of Nanomedicine
Synthesis and Characterization of Ultrafine and Porous Structure of Magnesium Ferrite Nanospheres
Porous sphere-shaped magnesium (MgFe2 O4 ) spinel ferrite particles were synthesized with high yields, crystallinity and purity through an easy, quick, reproducible and low-temperature hydrothermal synthesis route starti...
Crystallization of Amorphous Iron Nanoparticles by Means of Molecular Dynamics Simulation
Method of molecular dynamics (MD) simulation was applied to study the crystallization of the amorphous iron nanoparticles. The research sample is a sphere with a radius of 32.5Å under free boundary conditions. The mechan...