DEVELOPMENT AND EVALUATION OF PRONIOSOMES AS A PROMISING DRUG CARRIER TO IMPROVE TRANSDERMAL DRUG DELIVERY
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 11
Abstract
Drug delivery systems using colloidal particulate carriers such as liposomes and niosomes have distinct advantages over conventional dosage forms. However, there remain significant problems like instability in the general application of liposomes and niosomes for drug delivery. Proniosome have the potential to become a promising drug carrier in order to give stability to niosomal drug delivery system without interfering it,s meritorious properties. Proniosomes is dry formulation using suitable carrier coated with non ionic surfactants and can be converted into niosomes immediately before use by hydration. This article describes the detail of formulation and evaluation of Proniosome including morphology, particle size, particle size distribution and drug release and their advantages over noisome. In all parameters proniosome are better than conventional niosomes.
Authors and Affiliations
Kapil Kumar, A. K. Rai
Keywords
Related Articles
- EP ID EP103301
- DOI -
- Views 114
- Downloads 0
AN OVERVIEW ON: PHARMACEUTICAL AEROSOLS
Pulmonary drug delivery system is found to have a wide range of application in the treatment of illness as well as in the research field due to its beneficial effect over the other dosage form. It is used not only in tre...
DEVELOPMENT AND EVALUATION OF NORFLOXACIN LOADED MALTODEXTRIN BASED PRONIOSOMES
Controlled release drug products are often formulated to permit the establishment and maintenance of drug concentration at target site for longer interval of time. One such technique of drug targeting is ‘niosome’. In or...
PATIENT SATISFACTION ON GENERAL, INTERVENTION AND COGNITIVE SERVICES AMONG RETAIL PHARMACIES IN KOTA KINABALU, MALAYSIA
The services of retail pharmacies in Malaysia are still lagging behind compared to those in some developed countries. Doctors are allowed to dispense prescription medication to their patients. Besides that, traditional C...
RENIN ANGIOTENSIN SYSTEM AND MALIGNANCY: A MINI REVIEW
Cancer is the leading cause of death worldwide (World Health Organization). Therapeutic strategies usually involve a combination of surgical ablation, radiotherapy and chemotherapy. Apart from conventional chemotherapy,...
ANTIULCER ACTIVITY OF PREMNA SERRATIFOLIA AGAINST ASPIRIN INDUCED GASTRIC ULCER MODEL
The present study was carried out to investigate antiulcer activity of methanolic bark extract of Premna serratifolia against aspirin induced gastric ulcer models of male wistar rats. In aspirin induced pylorus ligation...