Development and Validation of RP HPLC Method for Estimation of Vortioxetine in Bulk and Pharmaceutical Dosage Form
Journal Title: International Journal of Trend in Scientific Research and Development - Year 2019, Vol 3, Issue 6
Abstract
A rapid and precise reverse phase high performance liquid chromatographic method has been developed for the validated of Vortioxetine in its pure form as well as in tablet dosage form. Chromatography was carried out on ODS C18 4.6 x 250 mm, 5µm column using Acetonitrile And Methonal 70 30 as the mobile phase at a flow rate of 1.0 mL min, the detection was carried out at 274nm. The retention time of the Vortioxetine was 2.922 ±0.02min. The method produce linear responses in the concentration range of 20 µg ml of Vortioxetine. The method precision for the determination of assay was below 2.0 RSD. The method is useful in the quality control of bulk and pharmaceutical formulations. Rathod K. G | Bargaje G. S | Rathod G. R | Deshpande O. V "Development and Validation of RP-HPLC Method for Estimation of Vortioxetine in Bulk and Pharmaceutical Dosage Form" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-6 , October 2019, URL: https://www.ijtsrd.com/papers/ijtsrd28040.pdf Paper URL: https://www.ijtsrd.com/pharmacy/analytical-chemistry/28040/development-and-validation-of-rp-hplc-method-for-estimation-of-vortioxetine-in-bulk-and-pharmaceutical-dosage-form/rathod-k-g
Authors and Affiliations
Keywords
Related Articles
- EP ID EP669976
- DOI -
- Views 148
- Downloads 0
Higher Order Low Pass FIR Filter Design using IPSO Algorithm
This paper presents an optimal design of digital low pass finite impulse response FIR filter using Improved Particle Swarm Optimization IPSO . The design target of FIR filter is to approximate the ideal filters on the re...
Secure Data Deduplication with Dynamic Ownership Management in Cloud Storage
In this paper, we propose a novel server-side deduplication scheme for encrypted data. It allows the cloud server to control access to outsourced data even when the ownership changes dynamically by exploiting randomized...
Effect of Financial Ratios on Firm Performance Study of Selected Brewery Firms in Nigeria
The study assessed the effect of financial ratios on performance of Quoted Breweries firms in Nigeria. It made use of ex post facto research design. Data were gotten from secondary sources obtained from NSE fact books an...
A Case Study of Traumatic Wound Treated with Jatyadi Ghrita
Initial treatment of wound aims to prevent infection and early wound healing. Various treatment modalities are used for dressing of wounds keeping in mind good cosmetic outcome. Vagbhatta Acharya has also mentioned the e...
Department Management Application
Managing a department is very hard job and taking so much time it may be school department or university department. Using department management application any department can easily handle work related to department lik...