Development of Combined Genetic and Imaging Approaches for Differentiation of Cutaneous Malignant Melanoma and Benign Melanocytic Nevi
Journal Title: Journal of Advances in Medical and Pharmaceutical Sciences - Year 2016, Vol 9, Issue 3
Abstract
The morbidity and mortality rate is reduced by premature and exact diagnosis of melanoma, which is the deadliest type of skin cancer. Timely identification of melanoma needs extremely complex and subjective test and laboratory samples. It is not insignificant even for experienced dermatologists to identify, so lot of concentration must be given. Finding the difference between melanoma and mole is also an issue in the accuracy of clinical diagnosis of melanoma. Especially, early diagnosis of cutaneous melanoma is very hard for experienced dermatologists. Even though a lot of advanced imaging techniques and clinical diagnostic algorithms such as dermoscopy and the ABCD rule of dermoscopy respectively are available, clinical diagnosis of melanoma becomes very challenging. The accuracy is an issue of distress (estimated to be about 75--85%) especially with oblique pigmented lesions. Quantitative and objective evaluation of the skin lesion is achieved by the above methods with respect to the subjective clinical assessment. An effective diagnosis can be achieved by reducing the viewer variability’s found in dermatologists' examinations. In order to improve some of existing methods and budding new techniques to ease accurate, fast and reliable diagnosis of cutaneous melanoma. In this paper different types diagnostic system of melanoma namely, preprocessing feature extraction, feature selection and classification is explained. The results of feature selection were optimized from advanced classes of classification techniques; namely, Two weighted k-nearest neighbor (k-NN) classifiers (k = 1, 30), a decision tree (DT), and the Random Forest (RF) algorithm are employed. Support Vector Machine has been very effective in computer-based melanoma diagnosis studies in the literature.
Authors and Affiliations
S. Abdalla, N. Al-Aama
Keywords
Related Articles
- EP ID EP328537
- DOI 10.9734/JAMPS/2016/28336
- Views 58
- Downloads 0
Development of Combined Genetic and Imaging Approaches for Differentiation of Cutaneous Malignant Melanoma and Benign Melanocytic Nevi
The morbidity and mortality rate is reduced by premature and exact diagnosis of melanoma, which is the deadliest type of skin cancer. Timely identification of melanoma needs extremely complex and subjective test and labo...
Induction of Heme Oxygenase-1 Improves Glucose Tolerance and Enhances Insulin Sensitivity in Obese Diabetic Rats
Aims: Obesity is a worldwide problem. It is considered to be a major risk factor for many systemic diseases like type 2 diabetes mellitus (T2D), cardiovascular, renal and orthopedic diseases. Recent evidence has undersco...
In vitro Antioxidant and Anti-bacterial Properties of a Contraceptive Herbal Mixture of Zanthoxylum zanthoxyloides Lam (Rutaceae) Euphorbia hirta Linn (Euphorbiaceae) and Abrus precatorius L. (Leguminosae)
Objective: The objective of this research was to evaluate, comparatively, the anti-oxidant and anti-bacteria properties of the mixture and the individual plants to ascertain if there is need for the continuous use of the...
Factors Affecting Radioprotective Efficacy of Ocimum sanctum (Tulsi) Extract in Mice
Background: Oscimum sanctum (Tulsi) is well reported for its medicinal values in Ayurveda. Although several chemical radioprotectors have shown excellent protection under in vitro conditions, lack of acceptable efficacy...
Effects of a Hydro-ethanolic Extract of Scoparia dulcis on Systemic Inflammation and Cachexia in an Allergic Asthma Model
Background: Chronic allergic lung diseases, such as allergic asthma, are often marked by increased systemic inflammatory responses and cachexia co-morbidities. Objectives: The study aimed at evaluating the systemic anti...