Development of Thrombosis in Acute Lymphoblast Leukemia in Children
Journal Title: Здоров`я дитини - Year 2014, Vol 4, Issue 55
Abstract
Two-thirds of cases of acute lymphoblastic leukemia (ALL) accounts for the period of childhood. ALL is highly sensitive to chemotherapy. Among patients receiving modern therapy, the overall five-year survival is 80 to 86 %, and five-year event-free survival — 78–83 %. Although most of these patients are likely to be cured, but in a large number of them disease relapse occurs, or secondary tumor develops, or some other complications associated with the treatment, which eventually can lead to fatal consequences. Adverse events during and after treatment of ALL in children are one of the burning topics for today. So it is important to emphasize the overall risk for thrombosis in children with ALL, as well as to identify individuals at high risk for its development, to discuss the clinical guidelines for the treatment and reduction of this risk, as well as bring our own clinical cases.
Authors and Affiliations
L. Ya. Dubey, O. I. Dorosh, N. V. Dubey, I. P. Tsymbalyuk, G. V. Makukh, M. V. Sapuzhak
Keywords
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