Device Closure of Small Ventricular Septal Defects: When and Why?
Journal Title: BMH Medical Journal - Year 2014, Vol 1, Issue 3
Abstract
Ventricular septal defect (VSD) accounts for approximately 20-30 % of all forms of congenital heart disease (CHD). They were traditionally closed surgically in the past. The surgery though safe carries the risk of morbidity, complete heart block, wound infection and thoracotomy scar on the chest. On weighing the risk and benefit, the small VSDs were not submitted to surgery in the past. So for many years it has been taught that the small VSDs are to be left alone and surgery is not recommended. Many clinicians believed in spontaneous closure of VSDs. Hence they advised the parents to wait for spontaneous closure till the child is 9 years old. But what if the VSD does not close by 10 years is the question. Are they normal as grown up congenital heart (GUCH). The Jane Somerville GUCH unit showed that spontaneous closure occurred only in 10% between the age of 17 and 45 (mean - 27) years in small VSDs in adults. What is worth noting is about 25% had serious complications: infective endocarditis (11%), progressive aortic regurgitation (5%), age-related symptomatic arrhythmias (8.5%) like atrial fibrillation. This means that asymptomatic small VSDs in childhood is not necessarily benign during adult life. This raises the question, when we have a safe non-surgical device closure available to close the small VSDs, should we put the future lives of the young in danger by not giving the benefit of technology to them?
Pheochromocytoma
Pheochromocytoma arises from adrenal medulla, which actually comprises about 10 % of adrenal gland. Sympathochromaffin system is the major neuroendocrine system in the body, it contains 2 components. Symapthetic ne...
Congenital Short QT Syndrome
Congenital short QT syndrome (SQTS) is characterised by extremely short QT intervals, typically with QTc less than 330 ms and a propensity for life threatening ventricular arrhythmias and atrial fibrillation. The QT inte...
Developmental Disorders in Children – Importance of Parent Training Interventions
Childhood developmental disorders cause significant negative impact on the physical, intellectual and social-emotional development of an individual. Developmental disorders are common in pediatric practice and these chil...
Learning Disabilities in Children: Epidemiology, Risk Factors and Importance of Early Intervention
Children with learning disabilities have significant impairment in reading, writing and mathematics, in spite of normal intelligence and sensory abilities. In reading disability, children will have difficulties in phonem...
A Case Of Treatment Emergent Central Sleep Apnea
Treatment emergent central sleep apnea (CSA) is defined as the persistence or emergence of central apneas and hypopneas during the CPAP titration for the treatment of OSA. It is a main cause for no improvement with CPA...