DEXMEDETOMIDINE AS A SOLE ANAESTHETIC AGENT IN NEUROSURGICAL PROCEDURES
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2019, Vol 8, Issue 16
Abstract
BACKGROUND Dexmedetomidine is an alpha-2 agonist gaining popularity in neurosurgery due to its unique properties as a sedative, anxiolytic and anaesthetic sparing effects without respiratory depression. We designed this study to assess the efficacy of Dexmedetomidine as a sole anaesthetic agent in neurosurgical cases lasting less than 90 min on spontaneous ventilation. METHODS After ethical committee approval and informed consent, adult patients of either gender ASA 1 or 2 of age group 18-60 years undergoing neurosurgical procedures lasting less than 90 min were included. All patients received standardized premedication and induced with IV Inj Fentanyl 2 mcg/kg and Inj. Dexmedetomidine bolus 1 mcg/kg (Over 10 min). All patients were put on Hudson’s face mask on spontaneous ventilation with 4 L/min oxygen. All patients maintained only with Inj. Dexmedetomidine infusion at 0.4- 0.7 mcg/kg/hr titrated to response Parameters- Haemodynamics, Post Induction sedation scores, Blood glucose, Patient movement at various stimuli, postoperative SOCA scores, analgesic requirement for the first 6hrs after surgery were noted. Data collected accordingly. RESULTS There was a statistically significant fall in the heart rate, systolic, diastolic and mean blood pressure (p-0.000) during infusion of Dexmedetomidine. There was no reduction in arterial oxygen saturation, no significant change in blood glucose (p-0.900). There were eight events of movement during the procedure requiring administration of fentanyl. Recovery of all patients was good. The mean SOCA score was 8.7±1.4. Incidence of PONV and need for rescue analgesia were not there in most of the patients. CONCLUSIONS Dexmedetomidine was found to be a good to excellent sole anaesthetic agent in short neurosurgical procedures.
Authors and Affiliations
Kolati Vara Lakshmi Suneetha, Pabba Upender Gowd, Kakarla Swarna Latha
Keywords
Related Articles
- EP ID EP611652
- DOI 10.14260/jemds/2019/287
- Views 77
- Downloads 0
OESOPHAGEAL PERFORATION SECONDARY TO LEMON IMPACTION AND TWO OTHER CASES- A RARE CASE REPORT
We came across a case of 50 years old female with complaints of dysphagia and loss of appetite since 15 days. Flexible and rigid endoscopy was done along with HRCT Thorax, wherein foreign body was identified in lower 2/3...
MATURE CYSTIC SACROCOCCYGEAL TERATOMA IN A CHILD- A CASE REPORT
Sacrococcygeal Teratomas (SCT) are congenital neoplasms, composed of a wide diversity of tissues foreign to the anatomical site in which they arise, that develop early in foetal life. They attract attention bec...
HYPERURICAEMIA- AN INDEPENDENT PREDICTOR OF ACUTE STROKE AND ITS OPTIMAL LEVEL TO PREVENT STROKE
BACKGROUND Stroke ranks as a third most common cause of mortality in the world after ischaemic heart disease and malignancy in the elderly. The prevalence of hyperuricaemia in stroke is 35.2% in men and 8.7% in women in...
TO EVALUATE THE COMPARISON OF INTUBATING CONDITIONS USING FENTANYL PLUS PROPOFOL VERSUS NALBUPHINE PLUS PROPOFOL DURING FIBEROPTIC INTUBATION
BACKGROUND Awake nasal or oral flexible fiberoptic intubation (AFOI) is the airway management technique of choice in known or anticipated difficult airway, severe cervical stenosis, Chiari malformation, unstable cervical...
A SYNDROME OF EXTENSIVE PERIPAPILLARY MYELINATED NERVE FIBRES, HIGH IPSILATERAL MYOPIA AND REFRACTORY AMBYLOPIA
Myelinated retinal nerve fibers are rare developmental anomalies present in 0.5- 1% of all eyes. Occur due to myelination of ganglion cells beyond the lamina cribrosa during embryonic development. Reports of am...