Diabetes mellitus and exocrine pancreatic insufficiency (review of literature)
Journal Title: Міжнародний ендокринологічний журнал - Year 2018, Vol 14, Issue 1
Abstract
Currently, an increasing importance is given to the study of the problem of exocrine pancreatic insufficiency, which is observed in a significant number of patients with diabetes mellitus (DM) type 1 and 2 and can potentially affect the compensation of DM. The mechanism of reducing the external secretion of the pancreas in DM is associated with an imbalance of inhibitory and stimulating pancreatic secretion of hormones, with fibrosis of the gland as a result of diabetic angiopathy. In type 2 DM, the mechanisms that result from the metabolic syndrome are involved in the pathogenesis of exocrine pancreatic insufficiency. Enzyme replacement therapy should be considered as one of the promising methods of treating DM patients.
Authors and Affiliations
L. T. Daminova, S. U. Muminova
Keywords
Related Articles
- EP ID EP275703
- DOI 10.22141/2224-0721.14.1.2018.127093
- Views 45
- Downloads 0
Clinical experience of using herbal medicinal product Glucemedin in the comprehensive treatment of patients with type 2 diabetes mellitus
Background. The current task of treating patients with type 2 diabetes mellitus and dyslipoproteinemia is the analysis of efficiency of the combination of standard hypoglycemic agents with phytotherapeutic drugs, but inf...
Clinical and laboratory features of thyroid hormone replacement therapy in patients of the advanced age
Clinical and subclinical hypothyroidism are the one of the most common pathologies in the practice of endocrinologist after type 2 diabetes mellitus. Each year, in up to 5 % of patients, latent (subclinical) hypothyroidi...
Dynamics of Systemic Inflammation and Insulin Resistance in Patients with Type 2 Diabetes Mellitus and Coronary Heart Disease
This article presents the results of the research of the changes in systemic inflammation and insulin resistance in patients with type 2 diabetes mellitus and coronary heart disease treated with metformin and pioglitazon...
Optimization of Ultrasonography in Assessing the Heart and Blood Vessels Condition in Patients with Arterial Hypertension with or without Type 2 Diabetes Mellitus
The objective — to study the peculiarities of the heart and blood vessels condition in patients with essential hypertension (EH) with or without type 2 diabetes mellitus. Materials and methods. The study involved 134 pat...
Features of Thyroid Functional State in Patients with Type 2 Diabetes Mellitus and Obesity
We have observed 55 patients with diabetes mellitus (DM) type 2 and obesity without signs of thyroid function abnormality, as well as 60 patients with DM type 2 and obesity combined with overt or subclinical hypothyroidi...