Diabetic foot ulcers at a tertiary care hospital: A clinico-microbiological profile
Journal Title: Indian Journal of Microbiology Research - Year 2017, Vol 4, Issue 4
Abstract
Introduction: Diabetic foot ulcer is one of the most common complications and cause of morbidity in patients with diabetes mellitus (DM). This study aims to determine the clinical and microbiological profile of diabetic foot ulcers and to determine their susceptibility pattern. Materials and Method: The present study was conducted in the Department of Microbiology at a tertiary care centre. 150 patients with diabetic foot ulcers were included in the study over a period of two years between December 2014 to December 2016. Appropriate samples were collected and processed. Isolation and identification of bacterial and fungal cultures was done by conventional methods and antimicrobial susceptibility pattern was determined. Correlation between diabetic history, ulcer duration, grade of ulcer (assessed by Wagner scale) and rate of bacterial and fungal isolation was made. Statistical analysis was done by Chi square test, Fischer Exact test and Single proportion Z test using SPSS software. Results: In our study, 138/150 samples were culture positive (47 polymicrobial and 91 monomicrobial). A total of 207 isolates out of 150 samples were isolated (175 bacterial and 32 fungal isolates). Pseudomonas aeruginosa 27.4 % (48/175) followed by Staphylococcus aureus 19.4 % (34/175) were most common bacterial pathogens isolated. 21.3 % (32/150) of the samples were positive for fungal growth, of which Candida albicans 25 % (08/32) was most common fungi isolated. Significant fungal isolation (p value 0.023) was made from samples showing no bacterial growth and fungal positivity was significantly (p value 0.39) associated with long standing non healing grade IV ulcers. Conclusion: Our study stresses on the need to study the clinico- microbiological profile of diabetic foot ulcers and to determine their susceptibility pattern as prompt treatment will prevent devastating consequences such as sepsis and amputation.
Authors and Affiliations
Anjana Gopi, Faiza Samreen, Swati Jain
Keywords
Related Articles
- EP ID EP295836
- DOI 10.18231/2394-5478.2017.0089
- Views 104
- Downloads 0
Dengue infection: its prevalence with seasonal variations
Background: Dengue fever is emerging arbo-viral acute febrile illness, which is endemic in India. Continuous surveillance of dengue fever is important for the proper and timely institution of vector control measures. Wit...
Evaluation of antimicrobial resistance in urinary isolates of member of enterobacteriaceae among woman attending Tertiary Care Hospital
Introduction: 1. Urinary Tract Infections (UTIs) are one of the most common urogenital infections and affects all age groups including men, women and children worldwide. 2. Urinary tract infections are a major public hea...
Aerobic Bacteriological Profile from Wound Site Infections in Road Traffic Accident (RTA) Patients
Background: Infections of musculoskeletal injuries due to road traffic accidents, especially open fractures, continue to pose a challenge. There is limited information on the early bacterial contaminants of these wounds...
Prevalence of asymptomatic urinary tract infection due to escherichia coli among pregnant women attending ANC clinic at BRIMS teaching hospital
Introduction Urinary tract infection UTI due to Escherichia coli E coli is a common health problem among women Pregnant women are at increased risk from both symptomatic and asymptomatic UTI because of the physiologic ch...
A microbiological study of otomycosis
Aim of the study: To determine the fungi causing otomycosis and the associated bacterial pathogens in a rural set up in clinically suspected cases of otomycosis. Methodology: Ear swabs were collected from 100 clinically...