Diagnosis Dini Tuberkulosis pada Kontak Serumah dengan Penderita Tuberkulosis Paru melalui Deteksi Kadar IFN-γ
Journal Title: Kesmas: National Public Health Journal - Year 2014, Vol 9, Issue 1
Abstract
Tuberculosis remains a global problem. In 2012, Indonesia has the third biggest tuberculosis cases in the world. The national target in Case Detection Rate for tuberculosis in 2012 was 70%, whereas Jawa Tengah reached only 58.48%. This research aimed to find interferon (IFN) g level among households contact with tuberculosis patient that used a new screening method of finding tuberculosis cases. The research design was a two-year cohort study (2011 - 2013) took place in pulmonary community health centers Semarang. In the end of research, found 12 participants household contact and 13 participants nonhousehold contact. Wilcoxon test result showed significant differences IFN-g level between contact group and noncontact group (p value= 0.004). IFN-g among household contact group decreased in most cases (75%). Among household contact group showed 25% had a clinical symptom of tuberculosis. Microbiology diagnostic showed 100% had negative result in both group. Result of receiver operating characteristic IFN-g level toward clinical status, had value area under curve 70.4% (95% CI= 40.8%-99.9%). Cut off point of IFN-g value have optimal result in ³3.277, with sensitivity and specificity value 67.7%. IFN-g level test can be used in screening program to early detection of infected among household contact with new tuberculosis cases, as a pilot project in high prevalence of new tuberculosis cases.
Authors and Affiliations
Sri Andarini Indreswari, Suharyo Suharyo
Keywords
Related Articles
- EP ID EP330985
- DOI 10.21109/kesmas.v9i1.453
- Views 80
- Downloads 0
Influence of Household Environment and Maternal Behaviors to Upper Respiratory Infection among Toddlers
Upper respiratory infection (URI) in developing countries causes high morbidity among toddlers. Indonesia Health Ministry reported that non-pneumonia acute respiratory infection (ARI) increased by 2.6% from 2007 to 2011....
Exclusive Breastfeeding Intention among Pregnant Women
Exclusive breastfeeding intention is a mother’s intention to provide her baby only breast milk since the infant was born until at the age of 6 months. Intention in prenatal period is the direct affirmation of exclusive b...
Efektivitas Air Perasan Kulit Jeruk Manis sebagai Larvasida Nyamuk Aedes aegypti
Dengue hemorrhagic fever is transmitted by Aedes aegypti mosquito that can be prevented with temefos. Sustainable use affects on mosquito resistance and environmental damage. Therefore, it needs natural larvasides by usi...
The Impact of National Health Insurance Policy to the Implementation of Health Promotion Program on Public Health Center in Indonesia
National Health Insurance (NHI) Program has been implemented in Indonesia on January 2014. That program definitely brings some changes into managerial aspect in public health center (PHC). This study aimed to determine a...
The Use of Earthworms and Household Organic Waste Composting Length of Time
Composting with earthworms is composting process by involving earthmacroorganism. Cooperation between earthworms and microorganisms may impact on decomposition process done by the microorganisms as assisted by the existe...