Diagnosis of adrenal glands incidentaloma
Journal Title: Медичні перспективи - Year 2017, Vol 22, Issue 3
Abstract
In this study the results of examination and treatment of 91 patients with adrenal glands incidentaloma were analyzed. According to the results of the morphological study, adenomas were the most common (n=60). Among malignant tumors, ACC was detected in 7 patients, low and undifferentiated cancer – in 3 patients, sarcoma – in 2 patients and metastasis of cancer – in 4 patients. To assess the nature of the tumor, the following criteria were used: size and density according to CT. In 43 patients with neoplasms less than 4 cm in 9,3% of cases malignant adrenalomas occurred, at 4-6 cm (n=29) - in 17,2% of cases, more than 6 cm (n=19) - in 31,6%. In patients with ACC, 71,4% of tumors exceeded 6 cm, 28,5% - were within 4-6 cm, 14,1% - less than 4 cm. The frequency of detection of malignant incidentalomas increases in proportion to the growth of tumor size, and with a diameter of more than 4 cm it was 27,1%. Adrenal adenomas in 31.6% of cases were from 4 to 6 cm, and in 10% - more than 6 cm. Thus, the orientation only on the size of tumors did not provide enough convincing grounds for determining its malignant potential. High native density was noted in ACC (33.4±2.8 HU), ganglioneuroma (36.6 НU) and metastases of cancer (43.6±9.0 HU). Low density was found in adenomas (0.4±10.7 HU) and adrenal cysts (6.0±8.2 HU), p<0.05. The most informative method of investigation in adrenal incidentalomas was CT, with sensitivity in adenomas and cancers – 98,3% and 94,4% respectively, specificity – 82,4% and 84,6%.
Authors and Affiliations
O. B. Kutovoy, E. V. Zhmurenko, L. V. Kunyk
Keywords
Related Articles
- EP ID EP229900
- DOI 10.26641/2307-0404.2017.3.111925
- Views 99
- Downloads 0
Можливості імуногістохімічних досліджень у прогнозуванні відповіді на лікування та модифікації лікувальних заходів при люмінальних раках молочної залози (огляд літератури)
Возможности иммуногистохимических исследований в прогнозировании ответа на лечение и модификации лечебных мероприятий при люминальных раках молочной железы (обзор литературы). Бондаренко И.Н., Завизион В.Ф., Артеменко М....
Evaluation of life quality of patients with chronic hepatitis C
The article presents the adaptation data of the quality of life questionnaire (QOL) in patients with chronic viral hepatitis C (CVHC). Ball score of QOL of patients with CVHC was 5.09±1.04, 2nd group (with co-infection...
Comparative effectiveness of using resorbable membranes of polylactic acid and collagen in regeneration of bone defects in patients with periimplantitis
The article presents the results of comparative study of effectiveness of usage of separation membranes from polylactic acid (PLA) and collagen in carrying out targeted regeneration of bone tissue in 22 patients with per...
The mixed impact of chemical and physical factors on reproductive system of rats in conditions of cold stress
The results of experimental investigations on studying features of gonadotoxic effect of nitrobenzene (NB), methyl tertiary butyl ether (MTBE) and electromagnetic radiation (EMR) both in conditions of cold stress and in...
Changes of the level of galectin-3, β-2-microglobulin, albuminuria and end glycation products in patients with chronic heart failure and atrial fibrillation under the influence of treatment
The combination of chronic heart failure and atrial fibrillation is considered one of the most prognostically unfavorable alliances among cardiovascular diseases. Now the need for new markers as potential targets for the...