Diagnostic Accuracy of FNAC in Evaluation of Breast Lumps
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 2
Abstract
Background and objectives: This study was conducted to compare the diagnostic accuracy of fine needle aspiration cytology (FNAC)in differentiating the benign and malignant lesions of palpable breast lump with histopathological correlation. Methods: This study was conducted at MNR MEDICAL COLLEGE AND HOSPITAL, Sangareddy , Telangana. The study included 50 patients who presented with palpable breast lumps to the surgical out-patient department. Thorough physical examination was done and the patients were subjected to fine needle aspiration cytology of the palpable breast lump. The cytological examination was classified as: Insufficient sample - C1, Benign - C2, Probably Benign - C3, Suspicious of malignancy - C4, Malignant - C5.All these patients were subjected to open/excision biopsy followed by histopathological examination. The diagnostic accuracy of the fine-needle aspiration was then compared with the gold standard histopathology. Results: Most of the cases were of benign pathology of which Fibroadenoma were most common (64%). It was seen that all the patients were female patients in the age group of 15-75 years. Majority of the lumps were found to be in the upper outer quadrant (46%). The sensitivity of fine needle aspiration cytology was found to be 83.33% , The specificity 100%, Positive predictive value 100% and Negative predictive value 97.77% . Conclusion: In patients with a palpable breast lump fine needle aspiration cytology can help to rule out a malignant lesion. This can hence afford as a cost –effective method in diagnosing breast lesions. Also due to its good tolerability and high diagnostic accuracy the patient need not be subjected to further evaluation which helps in the psychological well being of the patient. But, FNAC results when negative or suspicious should be correlated with clinical examination and imaging findings to prevent false positives and false negatives. A diagnosis suspicious for malignancy should be confirmed by open biopsy.
Authors and Affiliations
Sumeera Farhath SK
Keywords
Related Articles
- EP ID EP213238
- DOI -
- Views 101
- Downloads 0
Risk Factors of Pancreatic Carcinoma in Rural Area: Case Control Study
The risk factors of pancreatic carcinoma was poorly understand, especially in our country as there were no proper studies done in our country. The main purpose of this study to know the risk factors of pancreatic carcino...
A Prospective Study to Evaluate Cardiac Functional Status in Permanent Pacemaker Implanted Patients at a Tertiary Care Centre
Our study aimed at finding the incidence of overt heart failure or asymptomatic left ventricular systolic/diastolic dysfunction and cardiac dyssynchrony in patients undergoing single or dual chamber cardiac pacing and it...
Correlations of serum level of 25(OH)D, Parathyroid Hormone (PTH) and Bone Mineral Density (BMD) among chronic patients of Spinal Cord Injury
Background: Patients with SCI show mostly osteopenia or osteoporosis of the hip and spine. Vitamin D deficiency and secondary hyperparathyroidism may contribute to development of osteoporosis in SCI cases. Method: A corr...
A Study of Trends in the Prevalence and Pattern of Non Medical use of Dependence Producing Drugs among Discharged Male Psychiatric Patients
Objective: In India the use of psychoactive dependence-producing drugs (DPD) for recreational, medical and social purpose probably goes back to prehistoric times. However, DPD also cause numerous mental and physical disa...
Development and effectiveness of scoring index mobile application for hemodialysis in renal failure
Aim and Objectives: 1. To develop a mobile application with the help of renal failure severity scoring system which is already develop in NSCB medical college Jabalpur for deciding on need for urgent dialysis. 2. To prop...