Diagnostic Accuracy of FNAC in Evaluation of Breast Lumps
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 2
Abstract
Background and objectives: This study was conducted to compare the diagnostic accuracy of fine needle aspiration cytology (FNAC)in differentiating the benign and malignant lesions of palpable breast lump with histopathological correlation. Methods: This study was conducted at MNR MEDICAL COLLEGE AND HOSPITAL, Sangareddy , Telangana. The study included 50 patients who presented with palpable breast lumps to the surgical out-patient department. Thorough physical examination was done and the patients were subjected to fine needle aspiration cytology of the palpable breast lump. The cytological examination was classified as: Insufficient sample - C1, Benign - C2, Probably Benign - C3, Suspicious of malignancy - C4, Malignant - C5.All these patients were subjected to open/excision biopsy followed by histopathological examination. The diagnostic accuracy of the fine-needle aspiration was then compared with the gold standard histopathology. Results: Most of the cases were of benign pathology of which Fibroadenoma were most common (64%). It was seen that all the patients were female patients in the age group of 15-75 years. Majority of the lumps were found to be in the upper outer quadrant (46%). The sensitivity of fine needle aspiration cytology was found to be 83.33% , The specificity 100%, Positive predictive value 100% and Negative predictive value 97.77% . Conclusion: In patients with a palpable breast lump fine needle aspiration cytology can help to rule out a malignant lesion. This can hence afford as a cost –effective method in diagnosing breast lesions. Also due to its good tolerability and high diagnostic accuracy the patient need not be subjected to further evaluation which helps in the psychological well being of the patient. But, FNAC results when negative or suspicious should be correlated with clinical examination and imaging findings to prevent false positives and false negatives. A diagnosis suspicious for malignancy should be confirmed by open biopsy.
Authors and Affiliations
Sumeera Farhath SK
Keywords
Related Articles
- EP ID EP213238
- DOI -
- Views 68
- Downloads 0
Spectrum of Histopathological Findings in Hysterectomy Specimens- A Retrospective – 5 Year Study
Background: Diseases of the female genital tract are extremely common and include complications of pregnancy, infections, tumors, and hormonally induced abnormalities. Hysterectomy is one of the most common surgical proc...
A Correlative Study of ECG Changes in Dengue Fever
Dengue is one of the most emerging viral diseases globally and it is classified as a major global health threat by world health organization (WHO).It is mosquito-borne viral infection caused by Flavivirus and transmitted...
A Prospective Observational study to Identify the Incidence and Predictors of difficult and Impossible Mask Ventilation
Background: Mask Ventilation is the most fundamental skill of airway management and it is vital for the conduct of general anaesthesia1 . Difficulties with airway management in relation to general anesthesia have been a...
FNAC and Histopathological Correlation of Salivary Gland Lesions in a Tertiary Care Hospital in Kanchipuram
Background: Fine needle aspiration cytology is an economically effective technique which is sensitive and specific in diagnosing salivary gland lesions. However histopathology of salivary gland lesions is still the final...
Combined Mammographic and Sonographic Evaluation of Palpable Breast Masses in Correlation With Histopathological Examination
Aim & Objectives: To evaluate the role of combined mammographic and sonographic imaging in patients with palpable masses of the breast. To correlate these findings with histopathological diagnosis (FNAC/ Biopsy). To prov...