Diagnostic and Prognostic Value of Neutrophil Lymphocyte Ratio in Patients with Acute Pancreatitis
Journal Title: European Archives of Medical Research - Year 2019, Vol 35, Issue 3
Abstract
Objective: Acute pancreatitis is an inflammatory disease of the pancreas with local and systemic complications, and high mortality and morbidity. A variety of scoring systems have been developed for the early detection of severe acute pancreatitis. However, they are not feasible enough to detect severe patients in the early period. This study aimed to investigate the relationship between neutrophil lymphocyte ratio (NLR) and etiology of acute pancreatitis, clinical presentation, early diagnosis of severe pancreatitis, length of hospital stay and complications. Methods: A total of 150 patients with acute pancreatitis and 36 age and gender matched healthy controls were included. NLR was calculated within the first 24 hours of admission to the hospital. The results were compared with disease etiology, activity indices, complications, and length of hospital stay. Results: In patients with acute pancreatitis, NLR levels (7.0±9.3) were found to be significantly higher than in the control group (1.8±0.6) (p<0.05). There was no statistically significant difference between biliary and non-biliary pancreatitis groups in terms of neutrophil, lymphocyte, NLR, CRP and sedimentation levels (p>0.05). Regarding Ranson’s criteria and Modified Glasgow Prognostic score, NLR was significantly higher in patients with severe pancreatitis (p<0.05). However, there was no similar correlation with Balthazar score. Conclusion: NLR was shown to increase in patients with acute pancreatitis as well as in other inflammatory conditions. NLR may be useful as an easily applicable parameter in the early diagnosis of disease and prediction of disease activity in patients with acute pancreatitis.
Authors and Affiliations
Jale Memmedova, Yasemin Gökden, Mine Adaş
Keywords
Related Articles
- EP ID EP549062
- DOI 10.4274/eamr.galenos.2019.29392
- Views 177
- Downloads 0
Giant Cell Arteritis
A 76-year-old lady presented to emergency department for left eye sudden visual loss, and fundoscopy found cherry-red spot over the central macula with attenuated retinal vessels. Central retinal artery occlusion (CRAO)...
The Sequencing of the Insulin-like Growth Factor 1 and Fibulin 5 Gene Variants in the Pre and Post-menopausal Women with Stress Urinary Incontinence
Objective: Urinary incontinence (UI) is defined as a social problem via involuntary incontinence. Genetic variations that occur especially in muscle and connective tissue can cause the susceptibility stress type UI. We a...
Two Cases; Extra-articular Synovial Chondromatosis of Flexor Compartments of the Wrist
Synovial chondromatosis is a benign synovial neoplasm. Its main characteristic is the formation of cartilaginous nodules in synovial joints, bursae and tendon sheath. It usually presents between the third and fifth decad...
Isolated Finding of Intermittent Compression of the Trochlear Nerve by a Dolichoectatic Basilar Artery
Vertebrobasilar dolichoectasia (VBD) is a rare disorder characterized by elongation and tortuosity of the vertebrobasilar arteries. Clinical manifestations can range from ischemic stroke and progressive compression of cr...
Retrospective Analysis of Tumor Location with Residue Rates in High-grade Glial Tumors
Objective: Glioblastoma is the most commonly seen and quite an aggressive type of primary brain tumor. Location of the tumor, age, and sex are important prognostic factors. The aim of this study was to present the retros...