Diagnostic application of SpyGlass in indeterminate stricture of hilar bile duct
Journal Title: Journal of Surgery : Concepts & Practice - Year 2023, Vol 28, Issue 4
Abstract
[Objective:] To investigate the diagnostic value of SpyGlass choledochoscopy system in indeterminate stricture of hilar bile duct. [Methods:] A retrospective analysis was conducted on 146 patients with indeterminate stricture of the hilar bile duct who underwent endoscopic retrograde cholangio-pancreatography (ERCP) and SpyGlass examinations at our hospital between January 2018 and December 2022. The study recorded the visual impressions of the lesions, direct visualization-guided biopsy pathology, and conventional brush cytology results obtained using SpyGlass system. The sensiti-vity, specificity, and accuracy of different diagnostic methods were compared, taking pathological diagnosis as the gold standard and considering long-term follow-up results as well. [Results:] Out of the 146 patients, the procedure was successful in 145 cases (99.3%). The average procedure time was （51.5±16.9） min. The sensitivity, specificity, and accuracy of SpyGlass visual impression diagnosis for indeterminate biliary stricture were 83%, 84%, and 83%, respectively, outperforming brush cytology results (47%, 100%, and 52%). The combination of visual diagnosis and SpyBite biopsy yielded sensiti-vity of 91%, specificity of 63%, and accuracy of 85%. Adverse events occurred in 24.7% of cases, all of which were clinically mild. [Conclusions:] SpyGlass choledochoscopy has a high accuracy and safety in differential diagnosis of indeterminate stricture of the hilar bile duct. Its widespread application is warranted.
Authors and Affiliations
Xianrong HU, Dangdang YANG, Jun WU, Yi ZHAO, Cui CHEN, Ting ZHANG, Bing HU
Keywords
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- EP ID EP750896
- DOI 10.16139/j.1007-9610.2023.04.012
- Views 59
- Downloads 0
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